TITLE

A Gut Feeling to Cure Diabetes: Potential Mechanisms of Diabetes Remission after Bariatric Surgery

AUTHOR(S)
Young Min Cho
PUB. DATE
December 2014
SOURCE
Diabetes & Metabolism Journal;Dec2014, Vol. 38 Issue 6, p406
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
A cure for type 2 diabetes was once a mere dream but has now become a tangible and achievable goal with the unforeseen success of bariatric surgery in the treatment of both obesity and type 2 diabetes. Popular bariatric procedures such as Roux-en-Y gastric bypass and sleeve gastrectomy exhibit high rates of diabetes remission or marked improvement in glycemic control. However, the mechanism of diabetes remission following these procedures is still elusive and appears to be very complex and encompasses multiple anatomical and physiological changes. In this article, calorie restriction, improved (3-cell function, improved insulin sensitivity, and alterations in gut physiology, bile acid metabolism, and gut microbiota are reviewed as potential mechanisms of diabetes remission after Roux-en-Y gastric bypass and sleeve gastrectomy.
ACCESSION #
100314268

 

Related Articles

Share

Other Topics