TITLE

Adherence to anti-retroviral therapy & factors associated with it: a community based cross-sectional study from West Bengal, India

AUTHOR(S)
Pahari, Sobha; Roy, Sitesh; Mandal, Alpana; Kuila, Shymal; Panda, Samiran
PUB. DATE
September 2015
SOURCE
Indian Journal of Medical Research;Sep2015, Vol. 142 Issue 3, p301
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background & objectives: Failure to adhere to anti-retroviral therapy (ART) can lead to a range of unfavourable consequences impacting upon people living with HIV (PLH) and society. It is, therefore, paramount that ART adherence is measured in a reliable manner and factors associated with adherence are identified. Lack of such data from West Bengal necessitated undertaking the current study. Methods: Participants were included during August-October, 2011 from three Drop-In-Centres (DICs) from the three districts of West Bengal, India. ART-adherence was calculated by using formula based on pill-count and records collected from ART-card in possession of each of the 128 consenting adult PLH. Information on self-reported adherence, socio-demography, and adherence influencing issues was also collected through interviewer-administered questionnaire. Results: Of the 128 PLH, 99 (77%) and 93 (73%) PLH had ≥90 per cent and ≥95 per cent adherence, respectively to ART. Conversely, subjective reporting captured much higher proportion of PLH as 'well adherent'; a finding having implications for ongoing ART programme. Factors, independently associated with poor adherence (<90%), were '7th to 12th month period of ART intake' (adjusted OR=9.5; 90% CI 1.9 - 47.3; p=0.02) and 'non-disclosure of HIV status to family members' (adjusted OR=4; 90% CI 1.3 - 13; p=0.05. Results at 95 per cent adherence cut-off were similar. Interpretation & conclusions: Enabling environment, which would encourage people to disclose their HIV status and in turn seek adherence partners from families and beyond and ongoing adherencecounselling appear to be important issues in the programme. Relevance of these study findings in wider context is conceivable.
ACCESSION #
110188559

 

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