TITLE

Reduced adherence to antiretroviral therapy among patients on antiretroviral therapy in Limpopo province, South Africa

AUTHOR(S)
MAKUA, T.
PUB. DATE
June 2015
SOURCE
African Journal for Physical, Health Education, Recreation & Dan;2015Supplement, Vol. 21, p107
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The purpose of this study was to explore the determining factors for reduced adherence to antiretroviral therapy (ART) for HIV positive patients on ART residing in Polokwane, in Limpopo Province of South Africa. This study made use of the generic qualitative research design and in-depth qualitative interviews to collect data from a purposive sample of patients who did not adhere to ART. Thematic content analysis was used to analyse the data collected from the 18 patients from four clinics in Polokwane offering ART to patients. The participants attributed their reduced adherence to service delivery, patients' socio-economic status and family factors. The socio-economic status such as unemployment and abuse of alcohol leading to forgetfulness to take ART was among the factors cited by participants. Failure to disclose the health status to the family was indicated as the reason for reduced adherence to the treatment. None or partial adherence can lead to the development of drug-resistant strains of the virus. Health education on ART would assist the patients with managing the stigmatisation. In order to increase the understanding of the effects of alcohol on the ART, a lot of efforts need to be put on educating the patients about such interaction.
ACCESSION #
110326526

 

Related Articles

  • A prospective study of predictors of adherence to combination antiretroviral medication. Golin, Carol E.; Liu, Honghu; Hays, Ron D.; Miller, Loren G.; Beck, C. Keith; Ickovics, Jeanette; Kaplan, Andrew H.; Wenger, Neil S. // JGIM: Journal of General Internal Medicine;Oct2002, Vol. 17 Issue 10, p756 

    Objective: Adherence to complex antiretroviral therapy (ART) is critical for HIV treatment but difficult to achieve. The development of interventions to improve adherence requires detailed information regarding barriers to adherence. However, short follow-up and inadequate adherence...

  • Self-reported signs of lipodystrophy by persons living with HIV infection. Dreezen, C.; Schrooten, W.; De Mey, I.; Goebel, F. D.; Dedes, N.; Florence, E.; Colebunders, R.; Eurosupport Study Group // International Journal of STD & AIDS;Jun2002, Vol. 13 Issue 6, p393 

    Objective: To identify risk factors for the development of lipodystrophy in HIV infected patients on highly active antiretroviral therapy.Methods: A survey among patients with HIV infection using an anonymous questionnaire was conducted in 10 European countries between...

  • Treatment of Mycobacterium avium Complex Immune Reconstitution Disease in HIV-1-Infected Individuals. Desimone, Joseph A.; Babinchak, Timothy J.; Kaulback, Kris R.; Pomerantz, Roger J. // AIDS Patient Care & STDs;Dec2003, Vol. 17 Issue 12, p617 

    Immune reconstitution disease caused by Mycobacterium avium complex (MAC) infection presenting shortly after the introduction of highly active antiretroviral therapy (HAART) has been reported with increasing frequency in persons with HIV-1 infection during the past several years. Several...

  • Long-Term Efficacy and Safety of Raltegravir Combined with Optimized Background Therapy in Treatment-Experienced Patients with Drug-Resistant HIV Infection: Week 96 Results of the BENCHMRK 1 and 2 Phase III Trials. Steigbigel, Roy T.; Cooper, David A.; Teppler, Hedy; Eron, Joseph J.; Gatell, Jose M.; Kumar, Princy N.; Rockstroh, Jurgen K.; Schechter, Mauro; Katlama, Christine; Markowitz, Martin; Yeni, Patrick; Loutfy, Mona R.; Lazzarin, Adriano; Lennox, Jeffrey L.; Clotet, Bonaventura; Jing Zhao; Hong Wan; Rhodes, Rand R.; Strohmaier, Kim M.; Barnard, Richard J. // Clinical Infectious Diseases;2/15/2010, Vol. 50 Issue 4, p605 

    BENCHMRK-1 and -2 are ongoing double-blind phase III studies of raltegravir in patients experiencing failure of antiretroviral therapy with triple-class drug-resistant human immunodeficiency virus infection. At week 96 (combined data), raltegravir (400 mg twice daily) plus optimized background...

  • Predictors of Virological Outcome and Safety in Primary HIV Type 1—Infected Patients Initiating Quadruple Antiretroviral Therapy: QUEST GW PROB3005. Hoen, Bruno; Cooper, David A.; Lampe, Fiona C.; Perrin, Luc; Clumeck, Nathan; Phillips, Andrew N.; Goh, Li-Ean; Lindback, Stefan; Sereni, Daniel; Gazzard, Brian; Montaner, Julio; Stellbrink, Hans-Jurgen; Lazzarin, Adriano; Ponscarme, Diane; Staszewski, Shlomo; Mathiesen, Lars; Smith, Don; Finlayson, Robert; Weber, Rainer; Wegmann, Laurence // Clinical Infectious Diseases;8/1/2007, Vol. 45 Issue 3, p381 

    Background. Initiation of antiretroviral therapy during primary human immunodeficiency virus (HIV)-1 infection may confer long-term benefit. Methods. After initiation of zidovudine, lamivudine, abacavir, and amprenavir therapy in patients in the QUEST cohort, predictors of virological outcome,...

  • HIV “Elite Controllers” Are Characterized by a High Frequency of Memory CD8+CD73+ T Cells Involved in the Antigen-Specific CD8+ T-cell Response. Carrière, Matthieu; Lacabaratz, Christine; Kök, Ayrin; Benne, Clarisse; Jenabian, Mohammad-Ali; Casartelli, Nicoletta; Hüe, Sophie; Hocqueloux, Laurent; Lelièvre, Jean-Daniel; Lévy, Yves // Journal of Infectious Diseases;May2014, Vol. 209 Issue 9, p1321 

    Human immunodeficiency virus type 1 (HIV-1) infection is characterized by chronic immune activation and suppressed T-lymphocyte functions. Here we report that CD73, both a coactivator molecule of T cells and an immunosuppressive ecto-enzyme through adenosine production, is only weakly expressed...

  • Home-Based HIV Care Linked to Increase Uptake Of Antiretroviral Therapy. Ball, H. // International Perspectives on Sexual & Reproductive Health;Dec2014, Vol. 40 Issue 4, p216 

    The article discuses a research study on the association of home-based HIV care with increased uptake of antiretroviral therapy among adults who make use of self-administered HIV tests, conducted in Blantyre, Malawi. The effects of home initiation of HIV care is assessed. The researchers...

  • Use of a Commercial HIV Co-Receptor Tropism Assay in Clinical Practice. McCarthy, Matthew W.; Genzen, Jonathan R.; Wilkin, Timothy J.; Singh, Harjot K. // AIDS Patient Care & STDs;Feb2015, Vol. 29 Issue 2, p53 

    The article presents the result of a retrospective chart review related to co-receptor tropism ordered in New York City HIV outpatient clinic from March 16-2009-February 14, 2012. The variables considered in this study include the demographic characteristics for HIV patients based on...

  • Decrease of Cytomegalovirus Replication in Human Immunodeficiency Virus Infected-Patients after... O'Sullivan, Cathal E.; Drew, W. Lawrence; McMullen, Dragana J.; Miner, Richard; Lee, Jeanette Y.; Kaslow, Richard A.; Lazar, James G.; Saag, Michael S. // Journal of Infectious Diseases;9/1/99, Vol. 180 Issue 3, p847 

    Focuses on the effect of highly active antiretroviral therapy (HAART) on cytomegalovirus replication among HIV infected patients. Baseline median characteristics of the patients following the therapy; Median log following the initiation of HAART; Results of immune reconstitution secondary to HAART.

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics