Life-table analysis of artificial insemination pregnancy rates for couples with male factor and idiopathic infertility

Suzuki, Kohta; Kasai, Tsuyoshi; Suzuki, Mariko; Miyake, Maki; fujie, Michiko; Mizuno, Kaoruko; Hirata, Shuji; Hoshi, Kazuhiko
March 2004
Reproductive Medicine & Biology;Mar2004, Vol. 3 Issue 1, p27
Academic Journal
In the summer of 2002, standard guidelines for the application of assisted reproductive technology were reported by a research group of the Ministry of Health, Labor and Welfare. The present study aimed to examine the relationship between the number of cycles of artificial insemination and the cumulative pregnancy rates according to the cause of infertility. Patients who experienced their first cycle of artificial insemination during the period of January 1999–December 2002 were included in the study and were divided into a male factor infertility group and an idiopathic infertility group. Cumulative pregnancy rates resulting from artificial insemination with the husband's semen were calculated by the life-table approach. During the study period, 139 couples entered the assisted reproduction program and underwent 581 cycles. Significant differences were observed in cumulative pregnancy rates between the two groups. It is recommended that couples with male factor infertility and who fail to conceive within six or seven cycles of intrauterine insemination, consider a modification of treatment strategy such as in vitro fertilization, because cumulative pregnancy rates of this group were reached at a plateau within six or seven cycles. In contrast, patients with idiopathic infertility, the cumulative pregnancy rates appeared to increase constantly with each subsequent cycle. It is important to consider modifications of treatment strategy in the light of the cause of infertility. (Reprod Med Biol 2004; 3: 27–31)


Related Articles

  • Acceptable pregnancy rate of unstimulated intrauterine insemination: a retrospective analysis of 17,830 cycles. Honda, Tetsuro; Tsutsumi, Mai; Komoda, Fumio; Tatsumi, Kenichi // Reproductive Medicine & Biology;Jan2015, Vol. 14 Issue 1, p27 

    Purpose: To evaluate the pregnancy rate (PR) of unstimulated intrauterine insemination (IUI). Methods: This was a retrospective study in a private fertility clinic. Between 2004 and 2013, a total of 4,045 women underwent 17,830 cycles of unstimulated IUI. The etiologies of subfertility in the...

  • Patients' preferences for intrauterine insemination or in-vitro fertilization. Van Weert, Janne-Meije; Van den Broek, Janneke; Van der Steeg, Jan Willem; Van der Veen, Fulco; Flierman, Paul A.; Mol, Ben W. J.; Steures, Pieternel // Reproductive BioMedicine Online (Reproductive Healthcare Limited;Oct2007, Vol. 15 Issue 4, p422 

    Patients' preferences for intrauterine insemination (IUI) relative to IVF were assessed using trade-off interviews, and the number of IUI cycles they would undergo before changing to IVF. A total of 73 couples undergoing IUI with a total of 111 interviews were included. Scenarios were offered...

  • Eight years' experience with an IVF surrogate gestational pregnancy programme. Raziel, Arieh; Schachter, Morey; Strassburger, Deborah; Komarovsky, Dafna; Ron-El, Raphael; Friedler, Shevach // Reproductive BioMedicine Online (Reproductive Healthcare Limited;Aug2005, Vol. 11 Issue 2, p254 

    The aim of this study was to retrospectively audit eight years' experience of an IVF surrogate gestational programme and to compare the outcome of surrogacy due lo absence of the uterus with surrogacy indicated for repeated IVF failure and recurrent abortions. A total of 60 cycles of IVF...

  • High-magnification ICSI overcomes paternal effect resistant to conventional ICSI. Hazout, André; Dumont-Hassan, Martine; Junca, Anne-Marie; Bacrie, Paul Cohen; Tesarik, Jan // Reproductive BioMedicine Online (Reproductive Healthcare Limited;Jan2006, Vol. 12 Issue 1, p19 

    Previous studies have shown that repeated intracytoplasmic sperm injection (ICSI) failures can be caused by a paternal effect. Other studies have suggested that ICSI results are compromised if morphologically abnormal spermatozoa are injected into oocytes. This study was undertaken to evaluate...

  • Pregnancy achieved by transfer of thawed day 3 embryos that had been frozen after assisted hatching: a case report. Haydardedeoğlu, Bülent; Kılıçdağ, Esra Bulgan; Bağış, Tayfun // Journal of the Turkish-German Gynecological Association;Mar2010, Vol. 11 Issue 1, p55 

    Assisted Hatching (AH) is performed to increase implantation rates in assisted reproductive techniques, especially recurrent implantation failure and older age group. AH can be performed to four different techniques as laser, mechanical, enzymatic, chemical methods. In the literature, there is...

  • Effective Combined Treatment.  // Fertility Weekly;7/7/2008, p5 

    The article presents a medical study to determine the effects of pertubation with lignocaine on the day before ovulation on pregnancy rate, conducted by G. Edelstam and colleagues in Sweden. The study involved 130 couples who were presented for vitro fertilization (IVF) after at least one year...

  • Pregnancy resulting from transfer of repeat vitrified blastocysts produced by in-vitro matured oocytes in patient with polycystic ovary syndrome. Weon-Young Son; Seok-Yoon Lee; Mi-Jeong Chang; San-Hyun Yoon; Ri-Cheng Chian; Jin-Ho Lim // Reproductive BioMedicine Online (Reproductive Healthcare Limited;Mar2005, Vol. 10 Issue 3, p398 

    This report describes a live birth produced from repeal vitrification and thawing of blastocysts derived from in-vitro matured (IVM) oocytes in a women with polycystic ovarian syndrome. Immature oocyte retrieval was performed on day 12 of her induced menstrual cycle. The patient was administered...

  • In Vitro Fertilization and Intracytoplasmic Sperm Injection for Couples with Unexplained... Takeuchi, Shigeto; Minoura, Hiroyuki // Journal of Assisted Reproduction & Genetics;Oct2000, Vol. 17 Issue 9, p515 

    Determines the best insemination technique in patients undergoing in vitro fertilization (IVF) after failed direct intraperitoneal insemination (DIPI) and the outcomes of intracytoplasmic sperm injection. Fertilization rates after IVF between cases of unexplained infertility after failing to...

  • Women With One Ovary May Still Achieve Pregnancy.  // Fertility Weekly;11/3/2003, p5 

    Highlights the results of the study performed by Safaa Al-Hasani and colleagues from Germany concluding that women with a single ovary may still achieve pregnancy after intracytoplasmic sperm injection or in vitro fertilization.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics