TITLE

Meeting the Iron Needs of Low and Very Low Birth Weight Infants

AUTHOR(S)
Domellöf, Magnus
PUB. DATE
December 2017
SOURCE
Annals of Nutrition & Metabolism;Dec2017, Vol. 71, p16
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Low birth weight (LBW), defined as a birth weight of <2,500 g, affects 16% of all newborns and is a risk factor for impaired neurodevelopment as well as adverse cardiovascular and metabolic outcomes, including hypertension. LBW infants include both term, small for gestational age infants and preterm infants. Most LBW infants have only marginally LBW (2,000-2,500 g). Recent advances in neonatal care have significantly improved the survival of very LBW (VLBW) infants (<1,500 g). LBW infants are at high risk of iron deficiency due to low iron stores at birth and higher iron requirements due to rapid growth. Using a factorial approach, iron requirements of LBW infants have been estimated to be 1-2 mg/kg/day, which is much higher than the requirements of term, normal birth weight infants, who need almost no dietary iron during the first 6 months of life. In VLBW infants, blood losses and blood transfusions related to neonatal intensive care, as well as erythropoietin treatment, will greatly influence iron status and iron requirements. The timing of umbilical cord clamping at birth is of great importance for the amount of blood transfused from the placenta to the newborn and thereby total body iron. Delayed cord clamping of LBW infants is associated with less need for blood transfusion, less intraventricular hemorrhage, and less necrotizing enterocolitis. Randomized controlled trials have shown that an iron intake of 1-3 mg/kg/day (1-2 mg for marginally LBW and 2-3 mg for VLBW) is needed to effectively prevent iron deficiency. There is some recent evidence that these levels of iron intake will prevent some of the negative health consequences associated with LBW, especially behavioral problems and other neurodevelopmental outcomes and possibly even hypertension. However, it is also important to avoid excessive iron intakes which have been associated with adverse effects in LBW infants.
ACCESSION #
131988573

 

Related Articles

  • Iron Nutriture of the Fetus, Neonate, Infant, and Child. Cerami, Carla // Annals of Nutrition & Metabolism;Dec2017, Vol. 71, p8 

    Iron is a key nutrient and is essential for the developing fetus, neonate, infant, and child. Iron requirements are high during early stages of life because it is critically important for the production of new red blood cells and muscle cells as well as brain development. Neonates, infants, and...

  • Meeting the Iron Needs of Low and Very Low Birth Weight Infants. Domellöf, Magnus // Annals of Nutrition & Metabolism;2017 Supplement 3, Vol. 71, p16 

    No abstract available.

  • all about iron. Murray, Michael T. // Better Nutrition;Mar2014, Vol. 76 Issue 3, p32 

    The article discusses the health benefits, deficiency and dietary food sources of iron in human health. It mentions the role of iron in the hemoglobin molecule of human red blood cells (RBC) and its function of transporting oxygen from lungs to body's tissues. It explores the factors which can...

  • Iron deficiency: The developing child at risk. O'Sullivan, Siobhan // World of Irish Nursing & Midwifery;Mar2013, Vol. 21 Issue 2, p41 

    No abstract available.

  • Iron deficiency anaemia... This practice profile is based on NS626 Derbyshire E (2012) Strategies to improve iron status in women at risk of developing anaemia. Nursing Standard. 26, 20, 51-57. Potter, Yvonne // Nursing Standard;2/6/2013, Vol. 27 Issue 23, p59 

    Having read a learning zone article, Yvonne Potter now feels better able to offer patients pre-pregnancy advice.

  • Iron and Cognitive Development: What Is the Evidence?. Larson, Leila M.; Phiri, Kamija S.; Pasricha, Sant-Rayn // Annals of Nutrition & Metabolism;Dec2017, Vol. 71, p25 

    The theoretical irreversible damage that iron deficiency and iron deficiency anemia can exert on child development makes a compelling argument for action to alleviate the burden. However, a critical analysis of evidence from iron interventions in early life is necessary to determine whether and...

  • Iron in Pregnancy - How Do We Secure an Appropriate Iron Status in the Mother and Child? Milman, Nils // Annals of Nutrition & Metabolism;Nov2011, Vol. 59 Issue 1, p50 

    Iron deficiency and iron deficiency anemia (IDA) during pregnancy are risk factors for preterm delivery, prematurity, and small for gestational age birth weight. Iron deficiency has a negative effect on intelligence and behavioral development in the infant. It is essential to prevent iron...

  • Iron supplementation. Smith, H. // Professional Nursing Today;2012, Vol. 16 Issue 6, p9 

    The article discusses the supplementation of iron in human physiology. It mentions its inherent part in proteins and enzymes that maintain better health. It also notes its vital role in the delivery and storage of oxygen in the body which is a constituent of haemoglobin, myoglobin and other...

  • Anemia Feropriva na Infância: uma Revisão para Profisionais da Atenção Básica. Ferraz, Sabrine Teixeira // Revista de Atencao Primaria a Saude;jan-mar2011, Vol. 14 Issue 1, p101 

    Nutritional anemia, according to the World Health Organization, is a state in which a low blood hemoglobin concentration is a consequence of deficiency of one or more essential nutrients, for any reason. Iron deficiency anemia is the principal nutritional condition worldwide, and it is estimated...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics