TITLE

Building a Human Brain for Research

AUTHOR(S)
Bitar, Maina; Barry, Guy
PUB. DATE
February 2020
SOURCE
Frontiers in Molecular Neuroscience;2/18/2020, Vol. 13, p1
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Graph: Figure 1 Multiple systems are possible for the use of reprogrammed human stem cells in the investigation of human brain development, function, and disease. Through the exploration of self-organizing capabilities of the brain, Lancaster et al. in 2013 established an iPSC-derived, 3D culture system that opened up new opportunities for modeling and exploring human brain development. The future of organoids could lead to the ability to create almost any system of brain connections, both within the brain as "assembloids" (Pasca, [25]), but also within the whole body wherever the brain is connected via the central and peripheral nervous systems.
ACCESSION #
141802949

 

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