TITLE

Determinants of Immune Reconstitution Inflammatory Syndrome in HIV Type 1-Infected Patients with Tuberculosis after Initiation of Antiretroviral Therapy

AUTHOR(S)
Breton, Guillaume; Duval, Xavier; Estellat, Candice; Poaletti, Xavier; Bonnet, Daniel; Mvondo, David Mvondo; Longuet, Pascale; Leport, Catherine; Vildé, Jean-Louis
PUB. DATE
December 2004
SOURCE
Clinical Infectious Diseases;12/1/2004, Vol. 39 Issue 11, p1709
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Immune reconstitution inflammatory syndrome (IRIS) occurred in 16 of 37 antiretroviral-naive patients who were treated subsequently for tuberculosis and human immuno-deficiency virus (H IV) type 1 infection. IRIS was related to increases in the CD4 cell percentage and in the ratio of CD4 cells to CD8 cells after 1 month of antiretroviral therapy and to dissemination of tuberculosis. These results have implications for the diagnosis of IRIS and the understanding of its pathogenesis.
ACCESSION #
15056179

 

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