Comparison of WHOQOL-BREF and SF-36 in patients with HIV infection

Ping-Chuan Hsiung; Chi-Tai Fang; Yu-Yin Chang; Mao-Yen Chen; Jung-Der Wang
February 2005
Quality of Life Research;Feb2005, Vol. 14 Issue 1, p141
Academic Journal
The purpose of the study was to evaluate the reliability and validity of the two generic instruments, the WHOQOL and the SF-36, for assessing health-related quality of life in 224 patients with HIV infection. The internal consistency ranged from 0.75 to 0.86 across the WHOQOL-BREF domains and from 0.72 to 0.93 across the SF-36 scales. The scores of all WHOQOL-BREF domains and SF-36 scales correlated positively with the measure of happiness, Sat-HRQOL and self-perceived health status, and correlated negatively with the number and intensity of symptoms. Patients with higher CD4 cell counts scored significantly higher on G4 (general health), three WHOQOL-BREF domains, seven SF-36 scales, and PCS (physical component summary). Patients with fewer symptoms and with less intensity of symptoms had significantly higher scores on all four domains of WHOQOL-BREF, eight scales, PCS, and MCS (mental component summary) of the SF-36 scale. The correlations between the physical, psychological, and social domains of the WHOQOL-BREF and PF (physical functioning), MH (mental health), and SF (social functioning) of the SF-36 were 0.51, 0.75, and 0.54, respectively. There is also good correlation between PCS of the SF-36 and the physical domain of the WHOQOL-BREF (r= 0.48), and between MCS and all four domains of the WHOQOL-BREF (rrange = 0.60-0.75). The WHOQOL-BREF domains showed fewer floor or ceiling effect than the SF-36 scales. We concluded that both the WHOQOL-BREF and the SF-36 are reliable and valid health related quality-of-life instruments in patients with HIV infection.


Related Articles

  • SELF-RATED EMOTIONAL HEALTH IN ADULTS WITH AND WITHOUT HIV. Vance, David E. // Psychological Reports;Feb2006, Vol. 98 Issue 1, p106 

    Affect is an important indicator of quality of life; unfortunately, many people with Human Immunodeficiency Virus (HIV) disease are vulnerable to depression and negative affect. In a secondary data analysis, 50 HIV-positive and 50 HIV-negative adults between 30 and 65 years old completed several...

  • QUALITY OF LIFE OF PEOPLE LIVING WITH HIV AND AIDS IN ESTONIA. Rüütel, Kristi; Uusküla, Anneli; Minossenko, Anastassia; Loit, Helle-Mai // Central European Journal of Public Health;2008, Vol. 16 Issue 3, p111 

    The assessment of quality of life is central to understanding how people's lives are affected by HIV infection. Estonia -- the smallest of three Baltic countries -- has experienced massive outbreak of HIV infection. Yet, little is known about the quality of life of HIV infected people in...

  • Quality of Life and Related Factors for People Living With HIV/AIDS in Northern Taiwan. Meei-Horng Yang, Benjamin; Yi-Ming Chen, Benjamin; In-Tian Kuo, Benjamin; Kwua-Yun Wang // Journal of Nursing Research (Taiwan Nurses Association);Sep2003, Vol. 11 Issue 3, p217 

    The purpose of this study was to identify the variables related to quality of life in the population of individuals living with HIV/AIDS (PLWHA) in Taiwan. Purposive sampling was used to identify subjects from the outpatient departments (OPD) of three teaching hospitals and one sexually...

  • Health-related quality of life in HIV-1-infected patients on HAART: a five-years longitudinal analysis accounting for dropout in the APROCO-COPILOTE cohort (ANRS CO-8). Protopopescu, Camelia; Marcellin, Fabienne; Spire, Bruno; Préau, Marie; Verdon, Renaud; Peyramond, Dominique; Raffi, François; Chêne, Geneviève; Leport, Catherine; Carrieri, Maria-Patrizia; Préau, Marie; Raffi, François; Chêne, Geneviève // Quality of Life Research;May2007, Vol. 16 Issue 4, p577 

    Background: The long-term efficacy of Highly Active Antiretroviral Therapies (HAART) has enlightened the crucial role of health-related quality of life (HRQL) among HIV-infected patients. However, any analysis of such extensive longitudinal data necessitates a suitable handling of...

  • Variations in self-rated health among patients with HIV infection. Mrus, Joseph M.; Schackman, Bruce R.; Wu, Albert W.; Freedberg, Kenneth A.; Tsevat, Joel; Yi, Michael S.; Zackin, Robert // Quality of Life Research;Apr2006, Vol. 15 Issue 3, p503 

    Purpose: To assess how patients with HIV who are enrolled in a clinical trials cohort rate their health and to compare their ratings with those of patients with HIV from 2 other cohorts: the HIV Cost and Services Utilization Study (HCSUS), and Adult AIDS Clinical Trials Group...

  • Health-related quality of life and virologic outcomes in an HIV clinic. Call, S. A.; Klapow, J. C.; Stewart, K. E.; Westfall, A. O.; Mallinger, A. P.; DeMasi, R. A.; Centor, R.; Saag, M. S. // Quality of Life Research;Sep2000, Vol. 9 Issue 9, p977 

    Objective: The purpose of this study was to describe the relationship between viral load and health-related quality of life (HRQOL) in a cohort of persons with human immunodeficiency virus (HIV) infection.Design: We evaluated HRQOL measurements in a clinical cohort of...

  • Growing Older with HIV: A Study of Health, Social and Economic Circumstances for People Living with HIV in Australia over the Age of 50 Years. Pitts, Marian; Grierson, Jeffrey; Misson, Sebastian // AIDS Patient Care & STDs;Jul2005, Vol. 19 Issue 7, p460 

    The advent of highly active antiretroviral therapy means that we now have people living with HIV/AIDS (PLWHA) living longer, many of them surviving into old age. There has been relatively little attention paid to people aging with HIV. This study reports on a group of Australian PLWHA aged 50...

  • Quality of life among patients receiving palliative care in South Africa and Uganda: a multi-centred study. Selman, Lucy E.; Higginson, Irene J.; Agupio, Godfrey; Dinat, Natalya; Downing, Julia; Gwyther, Liz; Mashao, Thandi; Mmoledi, Keletso; Moll, Tony; Sebuyira, Lydia Mpanga; Ikin, Barbara; Harding, Richard // Health & Quality of Life Outcomes;2011, Vol. 9 Issue 1, p21 

    Background: Quality of life (QOL) is a core outcome of palliative care, yet in African settings there is a lack of evidence on patients' levels of QOL. We aimed to describe QOL among patients with incurable, progressive disease receiving palliative care in South Africa and Uganda, to compare QOL...

  • Quality of life, characteristics and survival of patients with HIV and lymphoma. Diamond, Catherine; Taylor, Thomas H.; Anton-Culver, Hoda // Quality of Life Research;Mar2010, Vol. 19 Issue 2, p149 

    We sought to compare the quality of life (QOL), characteristics, and survival of patients with non-Hodgkin lymphoma (NHL) with and without human immunodeficiency virus (HIV) infection. Using the population-based cancer registry for Orange and San Diego Counties, We recruited 50 patients with HIV...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics