TITLE

Therapeutic Interventions for HIV Infection and Chronic Viral Hepatitis

AUTHOR(S)
Cooper, Curtis L.
PUB. DATE
July 2005
SOURCE
Clinical Infectious Diseases;7/1/2005 Supplement, Vol. 41, pS69
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Combination antiretroviral therapy reduces overall and liver-specific morbidity and mortality in coinfection with human immunodeficiency virus (HIV) and hepatitis C virus (HCV) and represents the most beneficial pharmaceutical treatment intervention for most coinfected patients. Antiviral therapy for HCV infection is potentially organ- and life-saving but, in general, should be reserved for patients who achieve suppression of HIV RNA and immune restoration from combination antiretroviral therapy or for patients with nadir CD4+ T lymphocyte levels of >350 cells/μL. Safe and virologically active treatment of coinfection with HIV and hepatitis B virus can be concurrently achieved by the use of combination antiretroviral therapy regimens containing lamivudine and/or tenofovir.
ACCESSION #
17230321

 

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