TITLE

Additives (excipients and preservatives)

PUB. DATE
September 2004
SOURCE
WHO Technical Report Series;2004, Issue 927, p52
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article presents the section of the World Health Organization guidelines on nonclinical evaluation of vaccines concerning additives. In case where a new additive is to be applied on vaccine clinical investigation, there is a need to perform first toxicity studies of the additive alone and it must be recorded. Its compatibility will all vaccine antigens should also be documented in addition to the toxicological profile of the final vaccine development with considerations on animal testing.
ACCESSION #
19839146

 

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