TITLE

The effects of Lactobacillus-fermented milk on lipid metabolism in hamsters fed on high-cholesterol diet

AUTHOR(S)
Chiu-Hsia Chiu; Tzu-Yu Lu; Yun-Yu Tseng; Tzu-Ming Pan
PUB. DATE
June 2006
SOURCE
Applied Microbiology & Biotechnology;Jun2006, Vol. 71 Issue 2, p238
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The objective of this study was to evaluate the effects of local Lactobacillus strains (NTU 101 and 102) on cholesterol-lowering effects in vivo. Thirty male hamsters were housed, divided into five groups, and fed on a cholesterol diet (5 g/kg diet) to induce hypercholesterolemia. Milk fermented by Lactobacillus paracasei subsp. paracasei NTU 101, Lactobacillus plantarum NTU 102, and Lactobacillus acidophilus BCRC 17010 was administrated for this study. After treatment with different fermented milk, blood was taken and liver was removed for the determination of lipoproteins, including total cholesterol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglyceride. Lactobacilli and bifidobacteria decreased (105) in the control group; when hamsters were fed on fermented milk, the number of lactobacilli (107–108) and bifidobacteria (105–107) was increased. Serum and liver total cholesterol levels were significantly reduced by about 26.4, 23.5, and 30.1% and by about 17.7, 15.9, and 13.4% when hamsters were given fermented milk. However, serum HDL-C and LDL-C were also reduced. The results of this study showed that the hypocholesterolemic effect of local Lactobacillus strains was attributed to its ability to lower serum and liver total cholesterol levels. Thus, local Lactobacillus strains could significantly increase probiotic count.
ACCESSION #
21055307

 

Related Articles

  • Dietary cholesterol, female gender and n-3 fatty acid deficiency are more important factors in the development of non-alcoholic fatty liver disease than the saturation index of the fat. Comhair, Tine M.; Garcia Caraballo, Sonia C.; Dejong, Cornelis H. C.; Lamers, Wouter H.; Eleonore Köhler, S. // Nutrition & Metabolism;2011, Vol. 8 Issue 1, p4 

    Background: The central feature of NAFLD is a disturbed fatty-acid metabolism with hepatic lipid accumulation. However, the factors that determine the severity of NAFLD, including the role of nutrition, gender, and plasma lipid levels, remain to be determined. Methods: High-fat diets (42 en%...

  • THE EFFECT OF SODIUM 2-PHENYLBUTYRATE IN EXPERIMENTAL ATHEROSCLEROSIS. Kritchevsky, David; Moyer, Arden W.; Tesar, Walter C.; McCandless, Robert F. J.; Logan, John B.; Brown, Raymond A.; Englert, Mary // Angiology;Apr1956, Vol. 7 Issue 2, p156 

    1. Sodium 2-phenylbutyrate, in the form of the pure salt and of compounded pills, was assayed for its hypocholesterolemic properties and for its effect on atherosclerosis in cholesterol-fed rabbits. 2. Serum cholesterol levels were significantly lowered in the animals on the pure salt (P < .01)...

  • False negative results in the Roche assay for HDL-cholesterol. Bakker, Andries J; Zijlstra, Appie; Leemhuis, Marten P // Annals of Clinical Biochemistry;Sep2003, Vol. 40 Issue 5, p572 

    Measurement of HDL-cholesterol is important in the risk evaluation of cardiovascular disease. Recently, we encountered a 61-year-old man with a negative result for HDL-cholesterol using the Roche assay. Further analysis revealed that this patient had a monoclonal Ig type IgMκ, with an...

  • Comparison of lipid and non-lipid markers of atherosclerosis in arterial versus venous blood. Palmer, Bruce; Watson, Linley E; Riggs, Mark W; Lawrence, Mark; Baisden, Clinton E; McNeal, Catherine J; Macfarlane, Ronald D // Annals of Clinical Biochemistry;May2003, Vol. 40 Issue 3, p286 

    Background: Early studies have suggested that there may be differences in the concentration of lipoprotein particles and their associated apolipoproteins in arterial and venous blood and that this gradient might explain a proclivity to develop atherosclerotic lesions. The aim of this study was...

  • Exposure and effectiveness of phytosterol/-stanol-enriched margarines. de Jong, N.; Zuur, A.; Wolfs, M. C. J.; Wendel-Vos, G. C. W.; van Raaij, J. M. A.; Schuit, A. J. // European Journal of Clinical Nutrition;Dec2007, Vol. 61 Issue 12, p1407 

    Background:Studies on effectiveness of phytosterol/-stanol-enriched margarines in the community have received low priority. For postlaunch monitoring purposes including risk–benefit analyses, it is needed to investigate both exposure and effectiveness of these margarines.Objective:To...

  • Serum amyloid A, C-reactive protein and remnant-like lipoprotein particle cholesterol in type 2 diabetic patients with coronary heart disease. Hamano, M; Saito, M; Eto, M; Nishimatsu, S; Suda, H; Matsuda, M; Matsuki, M; Yamamoto, S; Kaku, K // Annals of Clinical Biochemistry;Mar2004, Vol. 41 Issue 2, p125 

    Background: Serum amyloid A (SAA) and C-reactive protein (CRP) have been suggested to be involved in the process of coronary heart disease (CHD) and to be potential markers and/or predictors of CHD. Remnant-like lipoprotein particles (RLPs), which are regarded as atherogenic remnant lipoprotein,...

  • Influence of Genotype Lines, Age at Slaughter and Sexes on the Composition of Rabbit Meat. Polak, Tomaž; Gašperlin, Lea; Rajar, Alenka; Žlender, Božidar // Food Technology & Biotechnology;Jan-Mar2006, Vol. 44 Issue 1, p65 

    Chemical composition (water, proteins, ash, intramuscular fat, cholesterol, fatty acid composition), sensory characteristics and instrumental profiles (colour and texture) of lean rabbit meat were investigated. It originated from animals of three different lines of SIKA genotype (A -- mother...

  • Dual HDL/total cholesterol test: a single-tube, homogeneous assay for sequential measurement of HDL cholesterol and total cholesterol. Sampson, M. L.; Csako, G.; Remaley, A. T. // Annals of Clinical Biochemistry;Jul2000, Vol. 37 Issue 4, p479 

    The quantitation of cholesterol in lipoprotein subfractions is valuable in estimating the risk for coronary artery disease, but requires multiple tests. We describe a relatively simple procedure, referred to as the dual HDL/total cholesterol (DHT) assay, which allows the sequential measurement...

  • Natural remedies lower cholesterol. Soref, Anna // Natural Foods Merchandiser;Mar2005, Vol. 26 Issue 3, p86 

    Studies natural remedies for lowering cholesterol. Physiological functions of cholesterol; Health risks associated with high cholesterol; Diet programs that can help lower cholesterol; Recommended foods for lowering cholesterol.

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics