Antipsychotic Agents May Trigger Insulin Resistance in Children

January 2005
Journal of Psychosocial Nursing & Mental Health Services;Jan2005, Vol. 43 Issue 1, p12
Academic Journal
Shows that atypical antipsychotic agents commonly used to treat children with aggression, bipolar disorder and schizophrenia may trigger insulin resistance, according to a study conducted by researchers at the Johns Hopkins Children's Center. Methodology of the study; Findings of the study.


Related Articles

  • Effectiveness of second-generation antipsychotics: a naturalistic, randomized comparison of olanzapine, quetiapine, risperidone, and ziprasidone. Johnsen, Erik; A.^Kroken, Rune; Wentzel-Larsen, Tore; A.^Jørgensen, Hugo // BMC Psychiatry;2010, Vol. 10, p26 

    Background: No clear recommendations exist regarding which antipsychotic drug should be prescribed first for a patient suffering from psychosis. The primary aims of this naturalistic study were to assess the head-to-head effectiveness of first-line second-generation antipsychotics with regards...

  • Choking deaths: the role of antipsychotic medication. Ruschena, D.; Mullen, P. E.; Palmer, S.; Burgess, P.; Cordner, S. M.; Drummer, O. H.; Wallace, C.; Barry-Walsh, J. // British Journal of Psychiatry;Nov2003, Vol. 183, p446 

    Background: An increased risk of choking associated with antipsychotic medication has been repeatedly postulated.Aims: To examine this association in a large number of cases of choking deaths.Method: Cases of individuals who had died because of choking were...

  • Depot antipsychotics in the prophylaxis of bipolar affective disorder. Littlejohn, A.; Leslie, F.; Cookson, J.; Littlejohn, R // British Journal of Psychiatry;Dec94, Vol. 165, p827 

    Background: The efficacy of depot antipsychotic drugs in the prophylaxis of bipolar affective disorder was investigated.Method: Life charts were constructed for 18 outpatients with bipolar disorder receiving prophylactic treatment with depot medication. The durations of...

  • List of Drugs in Development for Neurodegenerative Diseases. Pogačić, Vanda; Herling, Paul // Neurodegenerative Diseases;2007, Vol. 4 Issue 6, p443 

    Background/Aims: Alzheimer’s disease (AD) is characterized by extracellular Aβ peptide deposition originating from amyloid precursor protein cleavage and intracellular neurofibrillary tangles resulting from pathological tau protein aggregation. These processes are accompanied by...

  • Effects of long-term treatment with antipsychotics on serum leptin levels. Herrán, Andrés; García-Unzueta, María Teresa; Amado, José Antonio; de la Maza, María Teresa; Álvarez, Concepción; Vázquez-Barquero, José Luis; Herrán, A; García-Unzueta, M T; Amado, J A; de La Maza, M T; Alvarez, C; Vázquez-Barquero, J L // British Journal of Psychiatry;Jul2001, Vol. 179, p59 

    Background: Abnormal regulation of the adipocyte-derived hormone leptin could play a role in body weight gain induced by antipsychotics.Aims: To study the effects of long-term antipsychotic treatment on leptin levels in patients with schizophrenia.Method:...

  • Clozapine rechallenge after an episode of 'neuroleptic malignant syndrome'. Weller, Michael; Kornhuber, Johannes; Weller, M; Kornhuber, J // British Journal of Psychiatry;Dec92, Vol. 161, p855 

    Nine out of 4044 patients admitted to our institution between 1987 and 1990 suffered an episode of NMS. Neuroleptic rechallenge using clozapine for persisting psychiatric illness was tolerated by eight patients. Clozapine was discontinued in one older, high-risk patient because recurrence of NMS...

  • Olanzapine and tardive dyskinesia. Woods, S. W. // British Journal of Psychiatry;Oct99, Vol. 175, p391 

    A letter to the editor is presented in response to the article "Randomised double-blind comparison of the incidence of tardive dyskinesia in patients with schizophrenia during long-term treatment with olanzapine or haloperidol," by C.M. Beasley and colleagues in volume 174.

  • Involvement of Basal Ganglia Network in Motor Disabilities Induced by Typical Antipsychotics. Chetrit, Jonathan; Ballion, Bérangère; Laquitaine, Steeve; Belujon, Pauline; Morin, Stéphanie; Taupignon, Anne; Bioulac, Bernard; Gross, Christian E.; Benazzouz, Abdelhamid // PLoS ONE;2009, Vol. 4 Issue 7, p1 

    Background: Clinical treatments with typical antipsychotic drugs (APDs) are accompanied by extrapyramidal motor sideeffects (EPS) such as hypokinesia and catalepsy. As little is known about electrophysiological substrates of such motor disturbances, we investigated the effects of a typical APD,...

  • Pharmacotherapy for bipolar disorder and concordance with treatment guidelines: survey of a general population sample referred to a tertiary care service. Paterniti, Sabrina; Bisserbe, Jean-Claude // BMC Psychiatry;2013, Vol. 13 Issue 1, p1 

    Background: Many new approaches have been adopted for the treatment of bipolar disorder (BD) in the past few years, which strived to produce more positive outcomes. To enhance the quality of care, several guideline recommendations have been developed. For study purposes, we monitored the...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics