TITLE

Light shed on battle against HIV

AUTHOR(S)
Check, Erika
PUB. DATE
August 2006
SOURCE
Nature;8/24/2006, Vol. 442 Issue 7105, p852
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article presents an insight into the immune system of the human body and its vulnerability to HIV. It has been point out that HIV triggers a natural mechanism that impairs the killer T cells, responsible for fighting the virus. The article reports that Medarex, a Princeton based company is working in the direction and testing a protein that interferes with the PD-1/PD-1 ligand partnership. The finding could also help in the treatment of other chronic viral diseases, such as hepatitis C.
ACCESSION #
22063474

 

Related Articles

  • Influence of Coinfection with Hepatitis C Virus on Morbidity and Mortality Due to Human Immunodeficiency Virus Infection in the Era of Highly Active Antiretroviral Therapy. Tedaldi, Ellen M.; Baker, Rose K.; Moorman, Anne C.; Alzola, Carlos F.; Furhrer, Jack; McCabe, Robert E.; Wood, Kathleen C.; Holmberg, Scott D. // Clinical Infectious Diseases;2/1/2003, Vol. 36 Issue 3, p363 

    To ascertain the impact of hepatitis C virus (HCV) infection on human immunodeficiency virus (HIV) disease progression and associated death in the era of highly active antiretroviral therapy (HAART), we examined mortality rates, the presence of other diseases, and antiretroviral use in an...

  • First Things First: Balancing Hepatitis C and Human Immunodeficiency Virus. Graham, Camilla S.; Koziel, Margaret James // Clinical Infectious Diseases;2/1/2003, Vol. 36 Issue 3, p368 

    Editorial. Comments on a study by Tedaldi and colleagues, about the coinfection of HIV and hepatitis C virus. Influence of coinfection on morbidity and mortality; Balancing the risks and benefits of treating each of these viral infections; Impact of the availability of highly active...

  • Hepatitis C Virus Infection-Related Morbidity and Mortality among Patients with Human Immunodeficiency Virus Infection. Monga, Harpreet K.; Rodriguez-Barradas, Maria C.; Breaux, Katharine; Khattak, Kamran; Troisi, Catherine L.; Velez, Maria; Yoffe, Boris // Clinical Infectious Diseases;7/15/2001, Vol. 33 Issue 2, p240 

    Presents a study that discussed the morbidity and mortality of Hepatitis C virus (HCV) infection among patients with HIV virus infection. Factors that might promote progression of HCV-related chronic liver disease and HIV disease; Demographic characteristics, seroprevalence and baseline...

  • Hepatitis C Virus/Human Immunodeficiency Virus Coinfection: Clinical Management Issues. Mayer, Kenneth H.; Poles, Michael A.; Dieterich, Douglas T. // Clinical Infectious Diseases;7/1/2000, Vol. 31 Issue 1, p154 

    Studies clinical management issues concerning hepatitis C virus (HCV)/HIV virus coinfection. Interrelationships between highly active antiretroviral therapy and HCV infection; Increase in the incidence of HCV infection among HIV-infected patients; Approaches to treatment of HCV infection in...

  • Peginterferon &Alfa;-2a improved the hepatitis C virologic response in concurrent HIV and chronic hepatitis C virus infections. Chung, R.T. // ACP Journal Club;Jan/Feb2005, Vol. 142 Issue 1, p10 

    The article reports that peginterferon &Alfa;-2a improved the hepatitis C virologic response in concurrent HIV and chronic hepatitis C virus infections. More patients in the peginterferon α2a plus ribavirin group than in the interferon α-2a plus ribavirin group had a virologie response...

  • Impaired Hepatitis C Virus-Specific T Cell Responses and Recurrent Hepatitis C Virus in HIV Coinfection. Kim, Arthur Y.; Schulze zur Wiesch, Julian; Kuntzen, Thomas; Timm, Joerg; Kaufmann, Daniel E.; Duncan, Jared E.; Jones, Andrea M.; Wurcel, Alysse G.; Davis, Benjamin T.; Gandhi, Rajesh T.; Robbins, Gregory K.; Allen, Todd M.; Chung, Raymond T.; Lauer, Georg M.; Walker, Bruce D. // PLoS Medicine;Dec2006, Vol. 3 Issue 12, p2324 

    Background Hepatitis C virus (HCV)-specific T cell responses are critical for spontaneous resolution of HCV viremia. Here we examined the effect of a lymphotropic virus, HIV-1, on the ability of coinfected patients to maintain spontaneous control of HCV infection. Methods and Findings We...

  • Viral disease tests: A changing arena. Lewis, Laurie; Gruber, William // Patient Care;2/28/1999, Vol. 33 Issue 4, p18 

    Reports on the availability of improved serology and molecular techniques for earlier diagnosis of viral infections. Quicker, safer, cost-effective laboratory methods; Diagnostic tests for hepatitis C, HIV, herpes infections, respiratory infections; Advantages offered by the diagnostic techniques.

  • Role of Liver Biopsy in the Evaluation of Hepatitis C Virus Infection in HIV Coinfection. Sterling, Richard K. // Clinical Infectious Diseases;4/15/2005 Supplement, Vol. 40, pS270 

    Hepatitis C virus (HCV) coinfection is common in patients infected with human immunodeficiency virus (HIV), because the viruses share common routes of transmission. With the marked increase in life expectancy of HIV-infected patients associated with the use of highly active antiretroviral...

  • Maintenance Therapy with Opium Tincture for Injecting Drug Users; Implications for Prevention from Viral Infections. Mehrjerdi, Zahra Alam; Zarghami, Mehran // Hepatitis Monthly;Apr2013, Vol. 13 Issue 4, p1 

    A letter to the editor is presented in response to the article in the previous issue related with viral infections.

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics