TITLE

Appetite control after weight loss: what is the role of bloodborne peptides?

AUTHOR(S)
Doucet, Éric; Cameron, Jameason
PUB. DATE
June 2007
SOURCE
Applied Physiology, Nutrition & Metabolism;Jun2007, Vol. 32 Issue 3, p523
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The literature presented in this paper argues that our limited ability to maintain energy balance in a weight-reduced state is the product of our difficulty in compensating for the weight loss-induced reduction in total energy expenditure. The end result, translated into the overwhelming complexity of preserving long-term weight loss, is presented as being a consequence of compromised appetite control. Given the present-day food landscape and the resultant susceptibility to passive overconsumption, the focus of this review will be on the peripheral (“bottom-up”) signals (leptin, PYY, ghrelin, and GLP-1) and the evidence highlighting their influence on feeding behaviour. As we continue studying paradigms of body mass reduction, specifically the data emerging from patients of bariatric surgery, it is becoming clearer that counter-regulatory adaptations, possibly through down-(leptin, PYY, and GLP-1) or upregulation (ghrelin) of peptides, have an impact on energy balance. In itself, food deprivation influences some of the peptides that ultimately provide the physiological input for the overt expression of feeding behaviour; these peripheral adaptations are expected to serve as feeding cues — cues that, in the end, can serve to compromise the maintenance of energy balance. In a potentially novel intervention to increase compliance to long-term reductions in energy intake, it is proposed that manipulating the pattern of food intake to favourably alter the profile of gastrointestinal peptides would lead to better dietary control.
ACCESSION #
25479915

 

Related Articles

  • Bowels control brain: gut hormones and obesity. Bewick, Gavin A. // Biochemia Medica;2012, Vol. 22 Issue 3, p283 

    Peptide hormones are released from the gastrointestinal tract in response to nutrients and communicate information regarding the current state of energy balance to the brain. These hormones regulate appetite, energy expenditure and glucose homeostasis. They can act either via the circulation at...

  • Insights into energy balance from doubly labeled water. Schoeller, D. A. // International Journal of Obesity;Dec2008 Supplement 7, Vol. 32, pS72 

    Obesity is defined as the excess storage of energy in the form of fat that results from imbalances between energy intake and expenditure. The study of the components of energy balance has undergone a significant advancement with the application of the doubly labeled water (DLW) method to the...

  • Adaptive thermogenesis can make a difference in the ability of obese individuals to lose body weight. Tremblay, A; Royer, M-M; Chaput, J-P; Doucet, É // International Journal of Obesity;Jun2013, Vol. 37 Issue 6, p759 

    The decrease in energy expenditure that occurs during weight loss is a process that attenuates over time the impact of a restrictive diet on energy balance up to a point beyond which no further weight loss seems to be possible. For some health professionals, such a diminished energy expenditure...

  • weight loss. Peters, Michael // BMA A-Z Family Medical Encyclopedia;2004, p803 

    An encyclopedia entry for "weight loss" is presented. It is a condition that occurs when energy intake is less than energy expenditure. It explains that a doctor should always be consulted for unexplained weight loss as this may indicate a person's failing health. Depression, anorexia nervosa,...

  • The effect of milk proteins on appetite regulation and diet-induced thermogenesis. Lorenzen, J; Frederiksen, R; Hoppe, C; Hvid, R; Astrup, A // European Journal of Clinical Nutrition;May2012, Vol. 66 Issue 5, p622 

    Background/objectives:There is increasing evidence to support that a high-protein diet may promote weight loss and prevent weight (re)gain better than a low-protein diet, and that the effect is due to higher diet-induced thermogenesis (DIT) and increased satiety. However, data on the effect of...

  • Suppressed thermogenesis as a cause for resistance to slimming and obesity rebound: adaptation or illusion? Dulloo, A. G. // International Journal of Obesity;Feb2007, Vol. 31 Issue 2, p201 

    The article comments on the article "Clinical Significance of Adaptive Thermogenesis," by G. C. Major and colleagues. Resistance to slimming and obesity recidivism occur because the patients revert back to the same lifestyle of gluttony that made them obese. There is considerable...

  • Can a Pill or Injection Help Us Eat Less and Burn More Calories? Trecroci, Daniel // Diabetes Health;Jul2006, Vol. 15 Issue 7, p22 

    The article provides information on the results of a British study published in the "International Journal of Obesity" on losing weight among overweight and obese persons. It was found that the hormone oxyntomodulin can increase energy expenditure to reduce calorie intake. The participants of...

  • MUSCULAÇÃO: ASPECTOS POSITIVOS PARA O EMAGRECIMENTO. de Paiva Montenegro, Léo // Revista Brasileira de Prescrição e Fisiologia do Exercício;jan/fev2014, Vol. 8 Issue 43, p100 

    Introduction: The bodybuilding has not been widely prescribed for weight loss programs. Obesity has reached increasing numbers and become a public health problem because of the physiological changes that leads to the disease state and generating greater risk of disease. Strength training is an...

  • DDR Offers Aerobic Benefits, Study Says. J. S. // Fitness Business Pro;Mar2008, Vol. 24 Issue 3, p28 

    The article reports on the aerobic benefits of Dance Dance Revolution (DDR), according to research commissioned by the American Council on Exercise in the U.S. The study found that a workout using DDR could result in a significant weight loss if used regularly. The focus of the research is on...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics