Sexual risk behaviour and HAART: a comparative study of HIV-infected persons on HAART and on preventive therapy in Kenya

Sarna, A.; Luchters, S. M. F.; Geibel, S.; Kaai, S.; Munyao, P.; Shikely, K. S.; Mandaliya, K.; van Dammd, J.; Temmerman, M.
February 2008
International Journal of STD & AIDS;Feb2008, Vol. 19 Issue 2, p85
Academic Journal
Unprotected sex (UPS) among persons receiving highly active antiretroviral therapy (HAART) remains a concern because of the risk of HIV-transmission. A cross-sectional study comparing the sexual risk behaviour of 179 people living with HIV/AIDS (PLHA) receiving HAART with that of 143 PLHA receiving preventive therapy (PT) with cotrimoxazole/isoniazid was conducted in Mombasa, Kenya. Forty-five percent of all participants were sexually active in the last six months. Participants receiving PT were more likely to report ≥2 partners (13% vs.1%; P = 0.006). Participants receiving PT reported more UPS with regular partners (odds ratio [OR]: 3.9; 95% confidence interval [CI]: 1.8–8.4) and also more sexually transmitted infections (STI) symptoms (OR: 1.7; 95% CI: 1.0–2.8; P = 0.059). More than 40% of all participants did not know the HIV-status of regular partners. Therefore, HAART was not associated with increased sexual risk behaviours though considerable risk of HIV-transmission remains. HIV-care services need to emphasize partner testing and consistent condom use with all partners.


Related Articles

  • A short-term intervention trial on HIV positive patients using a Sri Lankan classical rasayana drug - Ranahamsa Rasayanaya. Somarathna, K. I. W. K.; Chandola, H. M.; Ravishankar, B.; Pandya, K. N.; Attanayake, A. M. P. // AYU: An International Quarterly Journal of Research in Ayurveda;Apr-Jun2010, Vol. 31 Issue 2, p197 

    Rational use of Rasayana therapy, in the management of HIV infected individuals, could potentially stabilize the destructive control mechanisms, by modulating the psycho-neuro-endocrine-immune axis. The objective of the present study has been to determine the short-term effects of Ranahamsa...

  • Unemployment as a risk factor for AIDS and death for HIV-infected patients in the era of highly active antiretroviral therapy. Delpierre, C.; Cuzin, L.; Lauwers-Cances, V.; Datta, G. D.; Berkman, L.; Lang, T. // Sexually Transmitted Infections;Jun2008, Vol. 84 Issue 3, p183 

    Objectives: To assess the association between social situation and disease progression among patients diagnosed with HIV infection since the advent of highly active antiretroviral therapy (HAART), taking late testing into account. Methods: Prospective cohort study of adults diagnosed with HIV...

  • Highly Active Antiretroviral Treatment and Children. Nachman, Sharon // Clinical Infectious Diseases;11/15/2011, Vol. 53 Issue 10, p1035 

    The author reflects on the study related to the effectiveness of highly active antiretroviral treatment (HAART) in reducing the mortality of patients including children and adults affected with human immunodeficiency virus (HIV). He appreciates the authors of the study for conducting a well...

  • The effect of different combination therapies on oxidative stress markers in HIV infected patients in cameroon. Ngondi, Judith L; Oben, Julius; Forkah, David Musoro; Etame, Lucein Honore; Mbanya, Dora // AIDS Research & Therapy;2006, Vol. 3, p19 

    The study assessed the effect of some highly active antiretroviral therapies (HAART), used in the management of HIV/AIDS in Cameroon, on oxidative stress markers such as malondialdehyde (as TBARs), albumin, protein carbonyl content and protein sulfhydryls groups. 85 HIV positive patients (34.8...

  • Optimal timing for initiation of antiretroviral therapy: a prospective study on treatment naive HIV patients. Chakravarty, Jaya; Singh, Avinash; Singh, Anup; Rai, Madhukar; Gupta, Anoop; Agarwal, Amit; Sundar, Shyam // BMC Infectious Diseases;2012 Supplement, Vol. 12 Issue Supplment 1, p1 

    The article presents a prospective study on the optimal timing for initiation of antiretroviral therapy in naive HIV patients. The authors observed the immunological disease progression of patients for 1 year, which resulted to higher number of opportunistic infection in patients. They indicate...

  • Oral lesions among HIV seropositive individuals in an era of generic HAART: markers of HAART efficacy? Vasudevan, Janani; Sivasankar, Vaishnavi; Rao, Umadevi K.; Kumarasamy, Nagalingeswaran; Ranganathan, Kannan // BMC Infectious Diseases;2012 Supplement, Vol. 12 Issue Supplment 1, p1 

    The article presents a study on the prevalence of oral lesions among HIV seropositive individuals in India. The authors investigate the prevalence of oral lesions among HIV patients on Highly Active Antiretroviral Therapy (HAART). They state that patients under HAART have fewer orals lesions,...

  • Immune Activation While on Potent Antiretroviral Therapy Can Predict Subsequent CD4+ T-Cell Increases Through 15 Years of Treatment. Xinyan Zhang; Hunt, Peter W.; Hammer, Scott M.; Cespedes, Michelle S.; Patterson, Kristine B.; Bosch, Ronald J. // HIV Clinical Trials;Mar/Apr2013, Vol. 14 Issue 2, p61 

    Background: While persistent T-cell activation has been cross-sectionally associated with poor CD4+ T-cell restoration in HIV-infected individuals maintaining antiretroviral treatment (ART)-mediated viral suppression, it remains unclear whether CD8+ T-cell activation is of predictive effect on...

  • Epidemiological and clinical features, response to HART, and survival in HIV-infected patients diagnosed at the age of 50 or more. Nogueras, MaMercedes; Navarro, Gemma; Antón, Esperança; Sala, Montserrat; Cervantes, Manel; Amengual, MaJosé; Segura, Ferran // BMC Infectious Diseases;2006, Vol. 6 Issue 1, p159 

    Background: Over the last years, the mean age of subjects with HIV infection and AIDS is increasing. Moreover, some epidemiological and clinical differences between younger and older HIV-infected individuals have been observed. However, since introduction of HAART therapy, there are...

  • Impact of HIV Comprehensive Care and Treatment on Serostatus Disclosure among Cameroonian Patients in Rural District Hospitals. Suzan-Monti, Marie; Kouanfack, Charles; Boyer, Sylvie; Blanche, Jérôme; Bonono, Renée-Cécile; Delaporte, Eric; Carrieri, Patrizia M.; Moatti, Jean-Paul; Laurent, Christian; Spire, Bruno // PLoS ONE;Jan2013, Vol. 8 Issue 1, Special section p1 

    This work aimed to analyze the rate of disclosure to relatives and friends over time and to identify factors affecting disclosure among seropositive adults initiating antiretroviral therapy (ART) in rural district hospitals in the context of decentralized, integrated HIV care and task-shifting...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics