Infant HIV infection despite "universal" antenatal testing

Struik, S. S.; Tudor-Williams, G.; Taylor, G. P.; Portsmouth, S. D.; Foster, C. J.; Walsh, C.; Hanley, C.; Walters, S.; Smith, J. H.; Lyall, H.
January 2008
Archives of Disease in Childhood;Jan2008, Vol. 93 Issue 1, p59
Academic Journal
We reviewed the antenatal HIV testing history, clinical presentation and outcome of 25 infants diagnosed with HIV between 1 January 2001 and 31 December 2005 in a tertiary referral hospital in London. Of the 25 cases, 21 had received antenatal care in the UK. Twelve mothers had not had an antenatal HIV test, four had tested positive antenatally, while five had had a negative HIV test on antenatal booking, implying seroconversion in pregnancy. When mothers had not been diagnosed antenatally, infants presented with severe infections, which were fatal in six cases. The majority (65%) of the children have long-term neurological sequelae. HIV seroconversion is an important cause of infant HIV in the UK.


Related Articles

  • HIV infection among pregnant women in Bobo-Dioulasso, Burkina Faso: comparison of voluntary and blinded seroprevalence estimates. Meda, Nicolas; Zoundi-Guigui, Marie-Therese; Perre, Philippe van de; Alary, Michel; Ouangré, Amadou; Cartoux, Michel; Mandelbrot, Laurent; Viens, Pierre; Dabis, Francois; Meda, N; Zoundi-Guigui, M T; van de Perre, P; Alary, M; Ouangré, A; Cartoux, M; Mandelbrot, L; Viens, P; Dabis, F // International Journal of STD & AIDS;Nov1999, Vol. 10 Issue 11, p738 

    The objective of our study was to estimate the prevalence of HIV infection among pregnant women in Bobo-Dioulasso (Burkina Faso) according to 2 survey methods. Unlinked anonymous HIV screening was performed among women attending 2 antenatal clinics. Voluntary and confidential HIV counselling and...

  • Perinatal transmission rate of HIV infection in Amritsar (Punjab). Jindal, N.; Aggarwal, A. // Indian Journal of Medical Microbiology;Apr2006, Vol. 24 Issue 2, p146 

    Presents a study on the perinatal transmission rate of HIV infection and the various risk factors influencing the transmission in Amritsar, India. Risk factors associated with perinatal transmission of HIV; Controversy in the prevention of transmission by elective caesarian section; Percentage...

  • Testing for hepatitis B in pregnancy.  // New Zealand Doctor;5/18/2005, p24 

    Presents information on additional antenatal screening tests required for pregnant women with chronic hepatitis B. Test which confirms chronic infection; Need for pregnant women to be checked for hepatitis B replication; Significance of additional testing.

  • Opt in or opt out: What is optimal for prenatal screening for HIV infection? Walmsley, Sharon // CMAJ: Canadian Medical Association Journal;3/18/2003, Vol. 168 Issue 6, p707 

    Discusses how the use of antiretroviral therapy with elective cesarean section has decreased the risk of mother-to-child transmission of HIV. Importance of formula feeding; Cost-effectiveness of screenings; Rates of testing in the provinces of Canada; Consideration of the opt-in and opt-out...

  • Evidence for population level declines in adult HIV prevalence in Kenya. Cheluget, B.; Baltazar, G.; Orege, P.; Ibrahim, M.; Marum, L. H.; Stover, J. // Sexually Transmitted Infections;Apr2006 Supplement 1, Vol. 82, pi21 

    The HIV/AIDS epidemic in Kenya has been tracked through annual sentinel surveillance in antenatal clinics since 1990. The system started with 13 sites and now has over 35. Behaviours have been measured through national Demographic and Health Surveys in 1993, 1998, and 2003. The surveillance data...

  • Reduction of mother-to-child transmission of HIV infection: non-pharmaceutical interventions and their implementation. Gibb, Diana M // International Journal of STD & AIDS;Dec1998 Supplement 1, Vol. 9, p19 

    The article discusses the study on mother-to-child transmission of HIV infection conducted in Great Britain. It focuses on the effect of place of antenatal interview and the time of uptake on the acceptance of testing. Moreover, it also examines the cost effectiveness of the alternative...

  • To what extent could performance-based schemes help increase the effectiveness of prevention of mother-to-child transmission of HIV (PMTCT) programs in resource-limited settings? a summary of the published evidence. Touré, Hapsatou; Audibert, Martine; Dabis, François // BMC Public Health;2010, Vol. 10 Issue 1, p702 

    Background: In resource-limited settings, HIV/AIDS remains a serious threat to the social and physical well-being of women of childbearing age, pregnant women, mothers and infants. Discussion: In sub-Saharan African countries with high prevalence rates, pediatric HIV/AIDS acquired through...

  • INCORPORATING HIV EDUCATION AND COUNSELING INTO ROUTINE PRENATAL CARE: A PROGRAM MODEL. Mason, Judy; Preisinger, Joyce; Sperling, Rhoda; Walther, Virginia; Berrier, Jayne; Evans, Veronica // AIDS Education & Prevention;Summer1991, Vol. 3 Issue 2, p118 

    The article presents information on the inclusion of HIV education and counseling program into the routine prenatal care programs. Emergence of HIV infections as a major concern among pregnant women in New York City led medical personnel to boost programs that provide basic information to...

  • Should HIV tests be mandatory for pregnant women?  // Glamour;Sep95, Vol. 93 Issue 9, p153 

    Presents the results of a survey on whether or not HIV tests should be made mandatory for pregnant women. Perception of mandatory testing as violation of civil rights; Discriminatory requirement of HIV testing; Priority for society to protect the health of babies.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics