Associations between postnatal weight gain, change in postnatal pulmonary function, formula feeding and early asthma

Turner, S.; Zhang, G.; Young, S.; Cox, M.; Goldblatt, J.; Landau, L.; Le Souëf, P.
March 2008
Thorax;Mar2008, Vol. 63 Issue 3, p234
Academic Journal
Background: A study was undertaken to examine factors that might influence lung function during infancy and to test the hypothesis that change in weight during infancy is negatively associated with change in lung function. Methods: Weight, length and maximal flow at functional residual capacity (V'maxFRC) were measured at ages 1 and 12 months. V'maxFRC was adjusted for length. Asthma symptoms and age at introduction of formula feeds were identified from questionnaires. Groups were dichotomised by V'maxFRC at 1 month and change in V'maxFRC. Results: 154 infants were assessed at ages 1 and 12 months. The change in V'maxFRC was inversely associated with change in weight (r = -0.18, r² = 0.13, p'<0.001). The group with lower V'maxFRC at 1 month and reduced change in V'maxFBC over infancy had the greatest weight gain (p = 0.003) and increased risk for asthma symptoms by 3 years (p = 0.017) but not afterwards. Exclusive breast feeding to 6 months was associated with a mean reduction in weight gain at age 12 months in comparison with earlier introduction of formula milk (mean difference 0.65 kg, p = 0.001), and was also associated with reduced asthma symptoms at 3 years (odds ratio 0.44, p = 0.043) but not at 6 or 11 years of age. Conclusions: Weight gain in infancy is inversely associated with change in lung function during infancy. Postnatal weight gain may be indirectly associated with early transient asthma symptoms via an influence on lung growth during infancy, and this is potentially modifiable by breast feeding. These associations could be relevant to the clinically recognised syndrome of the "fat happy wheezer".


Related Articles

  • Postnatal factors associated with failure to thrive in term infants in the Avon Longitudinal Study of Parents and Children. Emond, A.; Drewett, R.; Blair, P.; Emmett, P. // Archives of Disease in Childhood;Feb2007, Vol. 92 Issue 2, p115 

    Objective: To assess the contribution of postnatal factors to failure to thrive in infancy. Methods: 11 900 infants from the Avon Longitudinal Study of Parents and Children (ALSPAC), born at 37- 41 weeks' gestation, without major malformations and with a complete set of weight measurements in...

  • breast BUDDY. Kelly, Alice Lesch // Fit Pregnancy;Oct/Nov2007, Vol. 14 Issue 4, p144 

    The article discusses some of the reasons women seek help from a lactation consultant and how they learn to breastfeed like a pro. It cites several concerns of lactating mothers who breastfeed their babies like having sore nipples, breast infections and not producing enough milk. Given are tips...

  • Hematocrit Levels in Breast-Fed American Babies. Coulson, K. M.; Cohen, R. L.; Coulson, W. F.; D. B. Jelliffe // Clinical Pediatrics;Jul1977, Vol. 16 Issue 7, p649 

    The article cites a research study on hematocrit levels in breast-fed American babies. In the United States, over the past 10 years, breast feeding among mothers leaving hospital has risen from approximately 18 to 36 per cent. According to researchers total breastfeeding implies that 100 per...

  • Antenatal education and postnatal support strategies for improving rates of exclusive breast feeding: randomised controlled trial. Su, Lin-Lin; Chong, Yap-Seng; Chan, Yiong-Huak; Chan, Yah-Shih; Fok, Doris; Tun, Kay-Thwe; Ng, Faith S P; Rauff, Mary // BMJ: British Medical Journal (International Edition);9/22/2007, Vol. 335 Issue 7620, p596 

    ABSTRACT Objective To investigate whether antenatal breast feeding education alone or postnatal lactation support alone improves rates of exclusive breast feeding compared with routine hospital care. Design Randomised controlled trial. Setting A tertiary hospital in Singapore. Participants 450...

  • Poster Presentations Part II (pp. 627–727).  // Annals of Nutrition & Metabolism;Oct2009 Supplement 1, Vol. 55, p627 

    The article presents abstracts of various research on topics about eating and weight regulation, including the factors associated with bottle feeding practices in Pakistan, the determinants of exclusive breastfeeding among hospitalized infants in Bangladesh, and the conditions of health and...

  • your breastfeeding problems solved! Neifert, Marianne // Baby Talk;Aug2000, Vol. 65 Issue 6, p54 

    Answers several questions on breast feeding. Techniques in breastfeeding; Causes of pain while breast feeding; Information on mastitis; Details on supplemental infant formula milk.

  • Breastfeeding Patterns in the Rural Community of Hilo, Hawai'i:An Exploration of Existing Data Sets. Flood, Jeanie L. // Hawaii Journal of Medicine & Public Health;Mar2013, Vol. 72 Issue 3, p81 

    Before any breastfeeding promotion effort, an understanding of the existing breastfeeding patterns is essential. Hawai'i County is a rural, ethnically diverse, medically underserved community. The purpose of this study was to describe the breastfeeding patterns of women living in Hilo, Hawai'i....

  • MUMS IN NEED.  // Woman's Day (Australia Edition);12/1/2008, Vol. 60 Issue 48, p90 

    The article presents the suggestions given to a mother having difficulty in breastfeeding as her baby was diagnosed with gastro-oesophageal reflux. It advises to swaddling the baby to calm him. When it did not work, a dummy is offered, and once he was calm, the breast was reattached to him. It...

  • Factors Affecting Breastfeeding among Women of Mexican Origin or Descent in Los Angeles. Scrimshaw, Susan C. M.; Engle, Patricia L.; Arnold, Lola; Haynes, Karen // American Journal of Public Health;Apr87, Vol. 77 Issue 4, p467 

    Abstract: Data on breastfeeding intentions and behavior were collected in prenatal and postpartum interviews as part of a study on first birth among 518 women of Mexican origin or descent in two Los Angeles hospitals. The prenatal intentions of 82 per ¢ of the women to breastfeed were...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics