TITLE

Clinical and Virological Characteristics of Patients with Chronic Active Epstein-Barr Virus Infection Treated with Hematopoietic Stem Cell Transplantation: Insights and Questions

AUTHOR(S)
Gottschalk, Stephen
PUB. DATE
May 2008
SOURCE
Clinical Infectious Diseases;5/15/2008, Vol. 46 Issue 10, p1535
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article outlines the study which focuses on the largest cohort of patients in a single center who had severe chronic active Epstein-Barr virus (EBV) infection. These patients underwent hematopoietic stem cell transplantation. EBV is a latent g-herpesvirus, and 190% of the world's population is EBV positive. Most persons recover from the acute phase of primary EBV infection with no long-term sequelae. Interestingly, several of these diseases have unique geographic distributions, arguing that genetic and environmental factors play an important role in addition to EBV in their pathogenesis.
ACCESSION #
31779097

 

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