Coffee consumption and risk of type 2 diabetes, cardiovascular diseases, and cancer

van Dam, Rob M.
December 2008
Applied Physiology, Nutrition & Metabolism;Dec2008, Vol. 33 Issue 6, p1269
Academic Journal
Numerous epidemiological studies have evaluated the association between coffee consumption and risk of type 2 diabetes, coronary heart disease, and various cancers. This paper briefly reviews the evidence for a relation between coffee consumption and these conditions, with particular attention to methodological issues. Several early studies suggested that coffee consumption could result in a marked increase in risk of coronary heart disease and several types of cancer. However, more recent prospective cohort studies that are less prone to selection and information bias have not confirmed these findings. High consumption of unfiltered types of coffee, such as French press and boiled coffee, has been shown to increase low-density-lipoprotein-cholesterol concentrations. In addition, limiting caffeinated coffee intake during pregnancy seems a prudent choice. However, evidence has been accumulating that frequent consumption of coffee may reduce risk of type 2 diabetes and liver cancer. Further experimental studies are warranted to elucidate the underlying mechanisms and possibly identify the components in coffee that are responsible for these putative effects. In sum, the currently available evidence on coffee and risk of cardiovascular diseases and cancer is largely reassuring, and suggests that, for the general population, addressing other health-related behaviors has priority for the prevention of chronic diseases.


Related Articles

  • Coffee and Caffeine: The Relationship with Cancer, Diabetes, and Cardiovascular Disease / Café et caféine : le lien avec le cancer, le diabète et les maladies cardiovasculaires.  // Applied Physiology, Nutrition & Metabolism;Dec2008, Vol. 33 Issue 6, p1267 

    The article presents the study "Coffee and Caffeine: The Relationship with Cancer, Diabetes, and Cardiovascular Disease," which was delivered at the Canadian Society for Clinical Nutrition's Annual Meeting in June 2007 in Winnipeg, Manitoba.

  • Coffee Consumption Linked to Lower Diabetes Risk.  // Tufts University Health & Nutrition Letter;Feb2007, Vol. 24 Issue 12, p6 

    The article looks at two epidemiological studies using dietary questionnaires that suggest a protective effect against diabetes associated with coffee drinking. A U.S. study published in the "American Journal of Epidemiology," found that people who reported drinking four or more cups of coffee...

  • Coffee consumption and modality in women with cardiovascular disease. Lopez-Garcia, Esther; Rodriquez-Artalejo, Fernando; Li, Tricia Y.; Mukamal, Kenneth J.; Hu, Frank B.; van Dam, Rob M. // American Journal of Clinical Nutrition;Jul2011, Vol. 94 Issue 1, p218 

    Background: Coffee is commonly consumed among populations of all ages and conditions. The few studies that have examined the association between coffee consumption and mortality in patients with cardiovascular disease (CVD) have obtained conflicting results. Objective: The objective was to...

  • Long-term coffee consumption, caffeine metabolism genetics, and risk of cardiovascular disease: a prospective analysis of up to 347,077 individuals and 8368 cases. Zhou, Ang; Hyppönen, Elina // American Journal of Clinical Nutrition;Mar2019, Vol. 109 Issue 3, p509 

    Background Coffee is one of the most widely consumed stimulants worldwide and is generally considered to be safe or even beneficial for health. However, increased risk of myocardial infarction and hypertension has been suggested for individuals who carry a functional variant at cytochrome P450...

  • Coffee and health: what we still don't know. El-Sohemy, Ahmed // American Journal of Clinical Nutrition;Mar2019, Vol. 109 Issue 3, p489 

    An editorial is presented which discusses the effects of coffee and caffeine on health. It expresses concerns regarding its possible role in the occurrence of cardiovascular disease and heart attacks; association between coffee consumption and the risk of myocardial infarction, also the risk to...

  • Caffeine Buzz Greater in Small Doses.  // hfm (Healthcare Financial Management);Mar2007, Vol. 61 Issue 3, p24 

    The article reports on the study conducted by the researchers from Rush University Medical Center on the effects of drinking caffeine in the U.S. The researchers administered a low dose of caffeine hourly to a group of men. They have found that the level of caffeine in their bloodstreams...

  • Decaf less "de" than "caf".  // Fit Pregnancy;Apr2007, Vol. 14 Issue 1, p30 

    The article cautions pregnant women from drinking decaffeinated coffee since it still contain caffeine, according to researchers who sampled decaffeinated coffee from doughnut shops, fast-food restaurants and Starbucks. They found out that the coffee contains as much as 15.8 milligrams of...

  • Acute and Chronic Effects of Caffeine on Performance, Mood, Headache, and Sleep. James, Jack E. // Neuropsychobiology;1998, Vol. 38 Issue 1, p32 

    Despite being the most widely consumed psychoactive substance in the world, there is considerable confusion regarding the effects of caffeine. This study examined objective indices of performance, and self-reported mood, headache, and sleep in 36 healthy male and female habitual caffeine...

  • Caffeinated beverage intake and the risk of heart disease mortality in the elderly: a prospective analysis.  // American Journal of Clinical Nutrition;Feb2007, Vol. 85 Issue 2, p392 

    The article discusses the study which examines whether caffeinated beverages consumption shows protective effect against the risk of cardiovascular disease (CVD) mortality in older people. The study uses Cox regression analyses among 426 CVD deaths and involves a total of 6,594 participants with...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics