Early Medical Abortion Regimens Using Different Dosages of Mifepristone Are Equally Successful

K., Mahler
September 2000
Family Planning Perspectives;Sep/Oct2000, Vol. 32 Issue 5, p259
Academic Journal
This article focuses on early medical abortion regimens using different dosages of mifepristone are equally successful. A regimen of medical abortion consisting of 200 mg of mifepristone and 400 mg of misoprostol is as likely to successfully terminate an early pregnancy as a regimen using the same dosage of misoprostol and 600 mg of mifepristorie. In a study of treatment effectiveness conducted at 17 centers worldwide, 89% of women treated with the lower dose of mifepristone and 88% of those treated with the higher dose of the drug had a complete abortion. The proportion of women in each group who experienced side effects such as lower abdominal pain, nausea, vomiting and diarrhea was similar. The success of both of the regimens was related to gestational age--the risk of a continuing pregnancy was more than twice as high among women who received treatment 4-5 weeks after the expected date of menses as it was among those who were treated no more than 15 days after they missed their menstrual period. Eighty-nine percent of women who received the 200 mg dose of mifepristone and 88% of those who received the 600 mg dose had a complete abortion without surgical intervention.


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