Some evidence for improved metabolic control in type 1 diabetes in adolescents with addition of metformin to insulin therapy

July 2009
New Zealand Doctor;7/1/2009, p32
The article provides guidance whether the addition of metformin to insulin therapy is efficient in the management of type 1 diabetes mellitus among adolescents. According to evidence, the combined therapy lowered HbA1c levels more compared to insulin plus placebo treatment. A study also revealed a 10 percent decline in insulin dosage among patients who received combined therapy. Two of the cited side effects of the combined therapy are gastrointestinal upset and hypoglycemia.


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