The association between symptomatic, severe hypoglycaemia and mortality in type 2 diabetes: retrospective epidemiological analysis of the ACCORD study

Bonds, Denise E.; Miller, Michael E.; Bergenstal, Richard M.; Buse, John B.; Byington, Robert P.; Cutler, Jeff A.; Dudl, R. James; Ismail-Beigi, Faramarz; Kimel, Angela R.; Hoogwerf, Byron; Horowitz, Karen R.; Savage, Peter J.; Seaquist, Elizabeth R.; Simmons, Debra L.; Sivitz, William I.; Speril-Hillen, Joann M.; Sweeney, Mary Ellen
January 2010
BMJ: British Medical Journal (Overseas & Retired Doctors Edition;1/16/2010, Vol. 340 Issue 7738, p137
Academic Journal
The article focuses on a study which examined the association between symptomatic, severe hypoglycemia and mortality in type 2 diabetes using data from the Action to Control Cardiovascular Risk in Diabetes (ACCORD) study. The researchers observed a 2.8% rate of unadjusted mortality among patients in the intensive glucose control arm who had one or more episodes of hypoglacaemia requiring any assistance. The factors that could obscure the underlying cause of hypoglycaemia in the study are cited, including medication selection and titration.


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