TITLE

The association between symptomatic, severe hypoglycaemia and mortality in type 2 diabetes: retrospective epidemiological analysis of the ACCORD study

AUTHOR(S)
Bonds, Denise E.; Miller, Michael E.; Bergenstal, Richard M.; Buse, John B.; Byington, Robert P.; Cutler, Jeff A.; Dudl, R. James; Ismail-Beigi, Faramarz; Kimel, Angela R.; Hoogwerf, Byron; Horowitz, Karen R.; Savage, Peter J.; Seaquist, Elizabeth R.; Simmons, Debra L.; Sivitz, William I.; Speril-Hillen, Joann M.; Sweeney, Mary Ellen
PUB. DATE
January 2010
SOURCE
BMJ: British Medical Journal (Overseas & Retired Doctors Edition;1/16/2010, Vol. 340 Issue 7738, p137
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article focuses on a study which examined the association between symptomatic, severe hypoglycemia and mortality in type 2 diabetes using data from the Action to Control Cardiovascular Risk in Diabetes (ACCORD) study. The researchers observed a 2.8% rate of unadjusted mortality among patients in the intensive glucose control arm who had one or more episodes of hypoglacaemia requiring any assistance. The factors that could obscure the underlying cause of hypoglycaemia in the study are cited, including medication selection and titration.
ACCESSION #
47666709

 

Related Articles

  • Case Study: A 62-Year-Old Man With “Brittle” Type 1 Diabetes. Unger, Jeff // Clinical Diabetes;Winter2002, Vol. 20 Issue 1, p37 

    Presents a case study on a diabetic patient in the U.S. Conduction of self-monitoring blood glucose on the patient; Development of hypoglycemia aggravating the situation; Analysis on the result of the insulin infusion therapy and glucose monitoring tests conducted.

  • Managing diabetes at night.  // South Asian Post;12/13/2012, p6 

    The article discusses how diabetes patients can prevent nocturnal hypoglycemia, that includes testing blood sugar levels before going to sleep at night and maintaining a proper balance of insulin before bed, and taking a glucose tablet if the test shows low blood sugar levels.

  • Self-Monitoring of Blood Glucose: The Basics. Benjamin, Evan M. // Clinical Diabetes;Winter2002, Vol. 20 Issue 1, p45 

    Discusses the use of self-monitoring blood glucose (SMBG) therapy on treating diabetes in the U.S. Effectiveness of the method in preventing hypoglycemia; Function of SMBG in controlling blood sugar level; Use of SMBG data in modifying diabetes management regimen.

  • Glucose tester will lead to reduction in complications. Lewis, Colin // GP: General Practitioner;2/11/2002, p74 

    Features a blood sugar tester in Great Britain. Importance of glucose monitoring on diabetic control; Usefulness of the device on nocturnal hypoglycemia; Benefit of the technology on diabetics.

  • Persistent differences among centers over 3 years in glycemic control and hypoglycemia in a study of 3,805 children and adolescents with type 1 diabetes from the Hvidøre Study Group. Danne, Thomas; Mortensen, Henrik B.; Hougaard, Philip; Lynggaard, Helle; Aanstoot, Henk-Jan; Chiarelli, Francesco; Daneman, Denis; Dorchy, Harry; Garandeau, Patrick; Greene, Stephen A.; Hoey, Hilary; Holl, Reinhard W.; Kaprio, Eero A.; Kocova, Mirjana; Martul, Pedro; Matsuura, Nobuo; Robertson, Kenneth J.; Schoenle, Eugen J.; Sovik, Oddmund; Swift, Peter G.F. // Diabetes Care;Aug2001, Vol. 24 Issue 8, p1342 

    Objective: Twenty-one international pediatric diabetes centers from 17 countries investigated the effect of simple feedback about the grand mean HbA(1c) level of all centers and the average value of each center on changes in metabolic control, rate of severe hypoglycemia, and...

  • Glycemic Control and Hypoglycemia. Perlmuter, Lawrence C.; Flanagan, Brian P.; Shah, Parinda H.; Singh, Sant P. // Diabetes Care;Oct2008, Vol. 31 Issue 10, p2072 

    The article discusses the link between glycemic control and the risk of hypoglycemia among diabetic patients. The author comments on a study by Musen et al. which concluded that despite many severe hypoglycemic events, there was no measurable decline in cognition over ∼18 years. It notes...

  • Glycemic Goals in Diabetes: Trade-off Between Glycemic Control and Iatrogenic Hypoglycemia. Cryer, Philip E. // Diabetes;Jul2014, Vol. 63 Issue 7, p2188 

    The selection of a glycemic goal in a person with diabetes is a compromise between the documented upside of glycemic control--the partial prevention or delay of microvascular complications--and the documented downside of glycemic control--the recurrent morbidity and potential mortality of...

  • Evaluating the incidence, risk factors and glycaemic control of new-onset diabetes mellitus in kidney transplant recipients: a single centre study. Lai, Siok Wah; Chee Ping Chong; Aziz, Noorizan Abdul // Journal of Applied Pharmaceutical Science;Jun2013, Vol. 3 Issue 6, p44 

    This study aimed to evaluate the incidence and risk factors for development of post-kidney transplant diabetes mellitus (PTDM) and its glycaemic control in a single centre. Adult kidney transplant recipients (n = 164) under follow-up at Penang Hospital, Malaysia since transplantation (mean...

  • The impact of new guidelines for glucose tolerance testing on clinical practice and laboratory services. Lyon, Andrew W.; Larsen, Erik T.; Edwards, Alun L. // CMAJ: Canadian Medical Association Journal;10/26/2004, Vol. 171 Issue 9, p1067 

    Comments on the impact of new guidelines from the Canadian Diabetes Association in 2003 for glucose tolerance testing on the diagnosis of diabetes mellitus. Level of plasma glucose at risk for the disease; Limitations of the 2003 guidelines; Impact of guidelines on the delivery of laboratory...

  • Tool to Assess Likelihood of Fasting Glucose ImpairmenT (TAG-IT). Koopman, Richelle J.; Mainous III, Arch G.; Everett^2, Charles J.; Carter, Rickey E. // Annals of Family Medicine;Nov/Dec2008, Vol. 6 Issue 6, p555 

    The article examines the use of the Tool to Assess likelihood of fasting Glucose ImpairmenT (TAG-IT) to aid patients with diabetes in the U.S. Researchers analyze the patients' age, sex, body mass index (BMI), family history of diabetes, resting heart rate and history of hypertension. It states...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics