TITLE

Tigecycline resistance in Serratia marcescens associated with up-regulation of the SdeXY-HasF efflux system also active against ciprofloxacin and cefpirome

AUTHOR(S)
Hornsey, Michael; Ellington, Matthew J.; Doumith, Michel; Hudson, Sue; Livermore, David M.; Woodford, Neil
PUB. DATE
March 2010
SOURCE
Journal of Antimicrobial Chemotherapy (JAC);Mar2010, Vol. 65 Issue 3, p479
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Objectives: Efflux by RND-type transporters is known to confer resistance to tigecycline in several Enterobacteriaceae species and we examined the potential of this mechanism in Serratia marcescens using a clinical isolate and laboratory-selected mutants.
ACCESSION #
48045071

 

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