Mitochondrial bioenergetic adaptations of breast cancer cells to aglycemia and hypoxia

February 2010
Journal of Bioenergetics & Biomembranes;Feb2010, Vol. 42 Issue 1, p55
Academic Journal
The article discusses a study which conducted a longitudinal bioenergetic analysis of oxygen and glucose deprivation in human breast carcinoma cells and breast non-cancer cells. Neutral red assay was used to assess cell visibility. It suggests that cancer cells' metabolic apparatus eventually comprises interactions and coordination between nutrient sensing and oxygen sensing and explains the existence of two classes of tumors namely glycolic class and oxidative phosphorylation (OXPHOS) class.


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