TITLE

International Nonproprietary Names

AUTHOR(S)
Haselbeck, Anton
PUB. DATE
January 2010
SOURCE
WHO Drug Information;2010, Vol. 24 Issue 1, p21
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article discusses the biochemical properties of epoetins, which are recombinant versions of human erythropoietin. The carbohydrate structure and glycosylation process of epoetins are described. All epoetins irrespective of their International Nonproprietary Name (INN) exhibit distinct glycosylation patterns, due largely to different production processes. The author notes that even minor differences in glycosylation can have an impact on drug pharmacokinetics and safety.
ACCESSION #
51362756

 

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