TITLE

Cigarette smoking in middle age and a long-term risk of impaired activities of daily living: NIPPON DATA80

AUTHOR(S)
Takashima, Naoyuki; Miura, Katsuyuki; Hozawa, Atsushi; Okamura, Tomonori; Hayakawa, Takehito; Okuda, Nagako; Kadowaki, Takashi; Murakami, Yoshitaka; Kita, Yoshikuni; Nakamura, Yasuyuki; Okayama, Akira; Ueshima, Hirotsugu
PUB. DATE
September 2010
SOURCE
Nicotine & Tobacco Research;Sep2010, Vol. 12 Issue 9, p944
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Introduction: Few studies have reported the relationship between smoking in middle age and long-term risk of impaired activities of daily living (ADL). Methods: We analyzed 2,276 men and women aged 47-59 years at the baseline survey of NIPPON DATA80 in 1980. At the follow-up survey in 1999, ADL was surveyed among 1890 survivors. Multivariate-adjusted odds ratio (AOR) and 95% CI of impaired ADL or of composite outcome of either death or impaired ADL according to baseline smoking status were calculated by multiple logistic regression analyses. Results: In 1999, 386 participants were dead, and 75 participants had impaired ADL. Compared with nonsmokers, AOR (95% CI) of impaired ADL was significantly higher in current smokers at baseline (odds ratio [OR] 2.11 [1.09-4.06]). Compared with nonsmokers, AOR of impaired ADL was higher as the number of cigarettes increased (OR 2.04 [1.02-4.06] for <20 cigarettes/day and OR 2.35 [0.94-5.88] for >20 cigarettes/day; p for trend = .04). AOR of composite outcome for current smoking was 1.83 (1.37-2.41). Discussion: Smoking in middle age would increase future risks of impaired ADL. Smoking cessation may be important to prevent future impairment of ADL as well as death.
ACCESSION #
53376547

 

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