Maternal serum folate species in early pregnancy and risk of preterm birth

October 2010
American Journal of Clinical Nutrition;Oct2010, Vol. 92 Issue 4, p864
Academic Journal
The article presents a study which assesses the association between first-trimester maternal folate status as measured by 5-methyltetrahydrofolate (5MeTHF), 5-formyltetrahydrofolate (5FoTHF), and folic acid concentrations, and the risk of preterm birth and spontaneous preterm birth (sPTB). A cohort of 313 pregnant women were the subject of the study. It found a significant interaction between serum 5MeTHF and 5FoTHF concentrations and risk of preterm birth.


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