TITLE

Airflow limitation in morbidly obese, nonsmoking men

AUTHOR(S)
Rubinstein, I.; Zamel, N.; DuBarry, L.; Hoffstein, V.
PUB. DATE
June 1990
SOURCE
Annals of Internal Medicine;6/1/90, Vol. 112 Issue 11, p828
SOURCE TYPE
Academic Journal
DOC. TYPE
journal article
ABSTRACT
Study Objective: To determine the effect of obesity on pulmonary function.Design: Case-control study, using nonobese, age- and height-matched [corrected] nonsmokers.Setting: Metabolic and obesity clinics of two major teaching hospitals.Patients: One hundred and three obese, lifelong nonsmokers without cardiopulmonary disease.Controls: One hundred and ninety healthy, nonobese nonsmokers recruited from among hospital personnel.Measurements and Main Results: Complete pulmonary function measurements in all patients and controls. These measurements included maximum expiratory flow-volume curve, lung volumes and airway resistance using body plethysmograph, single-breath diffusing capacity for carbon monoxide, and total lung capacity using the helium dilution technique. Obese persons were found to have lower functional residual capacity, expiratory reserve volume, and total lung capacity by helium dilution than nonobese controls. In addition, residual volume and diffusing capacity were higher in the obese group. Finally, we found that obese men, but not women, had reduced maximum expiratory flow rates at 50% and 75% of exhaled vital capacity.Conclusion: Obesity may contribute independently of smoking habits to chronic airflow limitation in men.
ACCESSION #
6956155

 

Related Articles

  • Assessment of respiratory function in patients with podoconiosis Morrison, Chiara; Davey, Gail // Transactions of the Royal Society of Tropical Medicine & Hygiene;Mar2009, Vol. 103 Issue 3, p315 

    Summary: The respiratory effects of silicate particles have never been studied in patients with podoconiosis (a lower limb silicosis). We assessed whether lung function in patients differed from that of controls in the same silica-exposed environment. We assessed lung function using portable...

  • Lung decortication for chronic empyaema: effects on pulmonary function and thoracic asymmetry in the late period Gokce, Mertol; Okur, Erdal; Baysungur, Volkan; Ergene, Gokhan; Sevilgen, Gokcen; Halezeroglu, Semih // European Journal of Cardio-Thoracic Surgery;Oct2009, Vol. 36 Issue 4, p754 

    Abstract: Objective: Chronic empyaema deteriorates lung function and causes thoracic asymmetry due to intercostal narrowing in the diseased hemithorax. This study aims to investigate the rates of improvement in the pulmonary function tests (PFTs) and the thoracic deformity in late postoperative...

  • Pulmonary function tests in type 2 diabetes mellitus and their association with glycemic control and duration of the disease. Shah, Swati H.; Sonawane, Pranali; Nahar, Pradeep; Vaidya, Savita; Salvi, Sundeep // Lung India;Apr-Jun2013, Vol. 30 Issue 2, p108 

    Background: Pulmonary complications of diabetes mellitus (DM) have been poorly characterized. Some authors have reported normal pulmonary functions and even concluded that spirometry is not at all necessary in diabetic patients. Some studies have shown abnormal respiratory parameters in patients...

  • Pre- and post-bronchodilator lung function as predictors of mortality in the Lung Health Study. Mannino, David M.; Diaz-Guzman, Enrique; Buist, Sonia // Respiratory Research;Oct2011, Vol. 12 Issue 10, p1 

    Background: Chronic obstructive pulmonary disease (COPD) is supposed to be classified on the basis of postbronchodilator lung function. Most longitudinal studies of COPD, though, do not have post-bronchodilator lung function available. We used pre-and post bronchodilator lung function data from...

  • Direct visualisation of collateral ventilation in COPD with hyperpolarised gas MRI. Marshall, Helen; Deppe, Martin H.; Parra-Robles, Juan; Hillis, Susan; Billings, Catherine G.; Rajaram, Smitha; Swift, Andrew; Miller, Sam R.; Watson, Joanna H.; Wolber, Jan; Lipson, David A.; Lawson, Rod; Wild, Jim M. // Thorax;Jul2012, Vol. 67 Issue 7, p613 

    Background Collateral ventilation has been proposed as a mechanism of compensation of respiratory function in obstructive lung diseases but observations of it in vivo are limited. The assessment of collateral ventilation with an imaging technique might help to gain insight into lung physiology...

  • Evaluating systemic lupus erythematosus patients for lung involvement. Allen, D; Fischer, A; Bshouty, Z; Robinson, DB; Peschken, CA; Hitchon, C; El-Gabalawy, H; Meyers, M; Mittoo, S // Lupus;Oct2012, Vol. 21 Issue 12, p1316 

    Introduction: We set out to determine the frequency of respiratory symptoms, abnormal lung function, and shrinking lung syndrome (SLS) among patients with systemic lupus erythematosus (SLE) and to determine correlates of SLS. Methods: Consecutive adult patients who fulfilled the American College...

  • Efeitos negativos da insuficiência renal crônica sobre a função pulmonar e a capacidade funcional. Cury, Juliana L.; Aydos, Ricardo D. // Brazilian Journal of Physical Therapy / Revista Brasileira de Fi;mar/abr2010, Vol. 14 Issue 2, p91 

    Objective: To evaluate lung function and functional capacity in patients with chronic kidney failure (CKF) undergoing dialysis and in patients after kidney transplant. Methods: Seventy-two participants were evaluated: 32 patients with CKF on dialysis (DG) for at least six months, ten patients...

  • ESTIMATING RESPIRATORY MECHANICS WITH CONSTANT-PHASE MODELS IN HEALHTY LUNGS FROM FORCED OSCILLATIONS MEASUREMENTS. Ionescu, Clara; Desager, Kristine; de Keyser, Robin // Studia Universitatis Vasile Goldis Seria Stiintele Vietii (Life ;2009, Vol. 19 Issue 1, p123 

    Demanding minimal cooperation from the patient, the forced oscillation technique (FOT) is an attractive non-invasive lung function test. Its successful application to assess respiratory mechanics makes it an interesting topic for further investigations. Recent trends in signal processing and...

  • Lung volume and expiratory flow rates from pre- to post-puberty. Smith, Joshua; Emerson, Sam; Kurti, Stephanie; Gandhi, Kirti; Harms, Craig // European Journal of Applied Physiology;Aug2015, Vol. 115 Issue 8, p1645 

    Purpose: The purpose was to determine if the airways and lungs grow disproportionately from pre- to post-puberty in boys and girls. We hypothesized that the airways grow at a slower rate than lung volume (i.e. dysanapsis growth) during puberty and boys would exhibit more dysanaptic growth...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics