TITLE

Global: clinical trial shows dramatic reduction in transmission of HIV as a result of treatment

AUTHOR(S)
Cozac, David
PUB. DATE
October 2011
SOURCE
HIV/AIDS Policy & Law Review;Oct2011, Vol. 15 Issue 3, p31
SOURCE TYPE
Periodical
DOC. TYPE
Article
ABSTRACT
The article reports on a clinical trial conducted by the U.S. HIV Prevention Trials Network which revealed that human immunopdeficiency virus (HIV)-positive persons' adherence to an effective antiretroviral therapy reduce the risk of virus transmission by 96 percent. The trial confirmed that HIV treatment may reduce the HIV virus transmission. The results of the trial do not come without concerns about the legal and ethical implications of treatment as prevention.
ACCESSION #
69902552

 

Related Articles

  • Combined HIV prevention strategies work best for gay or straight couples.  // HIV Treatment ALERTS!;Nov2014, p3 

    The article presents a mathematical analysis at the Centers for Disease Control and Prevention (CDC). The study suggests that combining HIV prevention strategies, using antiretroviral therapy and the use of condoms, can offer the best long-term protection against HIV transmission in gay couples...

  • ART prevented HIV transmission in serodiscordant couples.  // Infectious Disease News;Jan2013, Vol. 26 Issue 1, p8 

    The article presents a study conducted by Chinese researchers, which showed that providing antiretroviral therapy (ART) to the HIV-positive partner in a serodiscordant couple lowered the rate of HIV transmission to the uninfected partner.

  • HPTN 071 (PopART): A Cluster-Randomized Trial of the Population Impact of an HIV Combination Prevention Intervention Including Universal Testing and Treatment: Mathematical Model. Cori, Anne; Ayles, Helen; Beyers, Nulda; Schaap, Ab; Floyd, Sian; Sabapathy, Kalpana; Eaton, Jeffrey W.; Hauck, Katharina; Smith, Peter; Griffith, Sam; Moore, Ayana; Donnell, Deborah; Vermund, Sten H.; Fidler, Sarah; Hayes, Richard; Fraser, Christophe // PLoS ONE;Jan2014, Vol. 9 Issue 1, p1 

    Background: The HPTN 052 trial confirmed that antiretroviral therapy (ART) can nearly eliminate HIV transmission from successfully treated HIV-infected individuals within couples. Here, we present the mathematical modeling used to inform the design and monitoring of a new trial aiming to test...

  • Characteristics of HIV-1 Serodiscordant Couples Enrolled in a Clinical Trial of Antiretroviral Pre-Exposure Prophylaxis for HIV-1 Prevention. Mujugira, Andrew; Baeten, Jared M.; Donnell, Deborah; Ndase, Patrick; Mugo, Nelly R.; Barnes, Linda; Campbell, James D.; Wangisi, Jonathan; Tappero, Jordan W.; Bukusi, Elizabeth; Cohen, Craig R.; Katabira, Elly; Ronald, Allan; Tumwesigye, Elioda; Were, Edwin; Fife, Kenneth H.; Kiarie, James; Farquhar, Carey; John-Stewart, Grace; Kidoguchi, Lara // PLoS ONE;2011, Vol. 6 Issue 10, p1 

    Introduction: Stable heterosexual HIV-1 serodiscordant couples in Africa have high HIV-1 transmission rates and are a critical population for evaluation of new HIV-1 prevention strategies. The Partners PrEP Study is a randomized, double-blind, placebo-controlled trial of tenofovir and...

  • Modeling of In-Utero and Intra-Partum Transmissions to Evaluate the Efficacy of Interventions for the Prevention of Perinatal HIV. Sripan, Patumrat; Le Coeur, Sophie; Amzal, Billy; Ingsrisawang, Lily; Traisathit, Patrinee; Ngo-Giang-Huong, Nicole; McIntosh, Kenneth; Cressey, Tim R.; Sangsawang, Suraphan; Rawangban, Boonsong; Kanjanavikai, Prateep; Tréluyer, Jean-Marc; Jourdain, Gonzague; Lallemant, Marc; Urien, Saïk // PLoS ONE;May2015, Vol. 10 Issue 5, p1 

    Background: Antiretroviral treatments decrease HIV mother-to-child transmission through pre/post exposure prophylaxis and reduction of maternal viral load. We modeled in-utero and intra-partum HIV transmissions to investigate the preventive role of various antiretroviral treatments...

  • Early Use of Antiretrovirals May Reduce HIV Transmission. Norman, Kayda // Applied Clinical Trials;Jun2011, Vol. 20 Issue 6, p17 

    The article discusses the findings of a study on a clinical trial known as the HPTN 052 in relation to the early use of oral antiretroviral therapy (ART). It states that the early use of ART may reduce the likelihood that a person with human immunodeficiency virus (HIV) will pass the virus to...

  • Failure to Identify HIV-infected Individuals in a Clinical Trial Using a Single HIV Rapid Test for Screening. Piwowar-Manning, Estelle; Fogel, Jessica M.; Laeyendecker, Oliver; Shauna Wolf; Cummings, Vanessa; Marzinke, Mark A.; Clarke, William; Breaud, Autumn; Wendel, Sarah; Lei Wang; Swanson, Priscilla; Hackett Jr., John; Mannheimer, Sharon; del Rio, Carlos; Kuo, Irene; Harawa, Nina T.; Koblin, Beryl A.; Moore, Richard; Blankson, Joel N.; Eshleman, Susan H. // HIV Clinical Trials;Mar/Apr2014, Vol. 15 Issue 2, p62 

    Background: In the HIV Prevention Trials Network (HPTN) 061 study, 8 (2.3%) of 348 HIV-infected participants identified as HIV uninfected at study enrollment using a single HIV rapid test for screening were found to be HIV infected after additional testing. Objectives: To evaluate the...

  • CD4[sup+] T Cell Count Recovery in HIV Type 1-Infected Patients Is Independent of Class of Antiretroviral Therapy. Khanna, Nina; Opravil, Milos; Furrer, Hansjakob; Cavassini, Matthias; Vernazza, Pietro; Bernasconi, Enos; Weber, Rainer; Hirschel, Bernard; Battegay, Manuel; Kaufmann, Gilbert R. // Clinical Infectious Diseases;10/15/2008, Vol. 47 Issue 8, p1093 

    Background. In recent years, treatment options for human immunodeficiency virus type 1 (HIV-1) infection have changed from nonboosted protease inhibitors (PIs) to nonnucleoside reverse-transcriptase inhibitors (NNRTIs) and boosted PI-based antiretroviral drug regimens, but the impact on...

  • Quick treatment of HIV helps halt the disease.  // Contemporary Sexuality;Jul2011, Vol. 45 Issue 7, p7 

    The article looks at a randomized clinical trial on the treatment of HIV-positive people which found that immediate treatment greatly reduces the spread of HIV.

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics