How HIV Treatment Failure Occurs Without Resistance

Breindl, Anette
September 2012
BioWorld Today;9/5/2012, Vol. 23 Issue 172, p1
The article reports on a mathematical model developed by scientists which may be able to help determine the best way to prevent resistance to currently available HIV drugs and identify effective combinations of new drugs early on in clinical development. According to Alison Hill of Harvard University, their model can predict the clinical significance of mutations in the context of drug combinations and different levels of patient compliance with their drug regimens.


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