Antiretroviral Therapy Given to Mother or Child Reduces Risk of HIV Transmission from Breast-Feeding

Melhado, L.
September 2012
International Perspectives on Sexual & Reproductive Health;Sep2012, Vol. 38 Issue 3, p167
Academic Journal
The article discusses a trial in women at a mother-to-child transmission prevention program to assess the relative effect of a 28-week antiretroviral prophylaxis during breast-feeding over absence of such an intervention to reduce the risk of mother-to-child HIV transmission for up to 48 weeks. The trial consisted of the maternal-antiretroviral group, the infant-nevirapine group and the control group. The risk of infant seroconversion was found to be higher in the control group than in either of the antiretroviral groups. Infant morbidity and mortality increased after cessation of breast-feeding and antiretroviral therapy. In light of the current WHO guidelines, continued breast feeding with antiretroviral prophylaxis given for an extended period could improve infant survival.


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