Piglets cloned from induced pluripotent stem cells

Fan, Nana; Chen, Jijun; Shang, Zhouchun; Dou, Hongwei; Ji, Guangzhen; Zou, Qingjian; Wu, Lu; He, Lixiazi; Wang, Fang; Liu, Kai; Liu, Na; Han, Jianyong; Zhou, Qi; Pan, Dengke; Yang, Dongshan; Zhao, Bentian; Ouyang, Zhen; Liu, Zhaoming; Zhao, Yu; Lin, Lin
January 2013
Cell Research;Jan2013, Vol. 23 Issue 1, p162
Academic Journal
The article focuses on experiments which demonstrate cloning of piglets from induced pluripotent stem cells (iPSCs). It is mentioned that two cell lines were induced from porcine bone marrow cells and porcine ear fibroblasts with a use of lentiviral vector. The experiments show that iPSCs from pigs can be used for nuclear transfer as donors by silencing of exogenous transcription factors by various methods.


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