TITLE

Effect of Zinc Sulfate Fortificant on Iron Absorption from Low Extraction Wheat Flour Co-Fortified with Ferrous Sulfate

AUTHOR(S)
Olivares, Manuel; Pizarro, Fernando; López de Romaña, Daniel
PUB. DATE
March 2013
SOURCE
Biological Trace Element Research;Mar2013, Vol. 151 Issue 3, p471
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The co-fortification of wheat flour with iron (Fe) and zinc (Zn) is a strategy used to prevent these deficiencies in the population. Given that Zn could interact negatively with Fe, the objective was to assess the effect of Zn on Fe absorption from bread prepared with wheat flour fortified with Fe and graded levels of Zn fortificant. Twelve women aged 30-43 years, with contraception and a negative pregnancy test, participated in the study. They received on four different days, after an overnight fast, 100 g of bread made with wheat flour (70 % extraction) fortified with 30 mg Fe/kg as ferrous sulfate (A) or prepared with the same Fe-fortified flour but with graded levels of Zn, as zinc sulfate: 30 mg/kg (B), 60 mg/kg (C), or 90 mg/kg (D). Fe radioisotopes (Fe and Fe) of high specific activity were used as tracers and Fe absorption iron was measured by the incorporation of radioactive Fe into erythrocytes. Results: The geometric mean and range of ±1 SD of Fe absorption were: A = 19.8 % (10.5-37.2 %), B = 18.5 % (10.2-33.4 %), C = 17.7 % (7.7-38.7 %), and D = 11.2 % (6.2-20.3 %), respectively; ANOVA for repeated measures F = 5.14, p < 0.01 (Scheffè's post hoc test: A vs D and B vs D, p < 0.05). We can conclude that Fe is well absorbed from low extraction flour fortified with 30 mg/kg of Fe, as ferrous sulfate, and up to 60 mg/kg of Zn, as Zn sulfate. A statistically significant reduction of Fe absorption was observed at a Zn fortification level of 90 mg Zn/kg.
ACCESSION #
85340420

 

Related Articles

  • ask the doc. Barnard, Neal D. // Vegetarian Times;Apr/May2012, Issue 393, p22 

    The article presents questions and answers on health including questions on how much iron a person needs on a daily basis and whether carbonated water increases the risk of osteoporosis.

  • Using dietary education to avoid iron deficiency in at risk patients. Jenkin, Gill // Primary Health Care;Apr2012, Vol. 22 Issue 3, p20 

    Anaemia is a worldwide problem, even in higher income countries. Insufficient iron in the diet can cause tiredness and hair loss, reduce fertility and impair mental and motor development in children. Healthcare professionals need to be able to recognise anaemia and have the knowledge to give...

  • Dietary Determinants of and Possible Solutions to Iron Deficiency for Young Women Living in Industrialized Countries: A Review. Beck, Kathryn L.; Conlon, Cathryn A.; Kruger, Rozanne; Coad, Jane // Nutrients;Sep2014, Vol. 6 Issue 9, p3747 

    Iron deficiency is a concern in both developing and developed (industrialized) countries; and young women are particularly vulnerable. This review investigates dietary determinants of and possible solutions to iron deficiency in young women living in industrialized countries. Dietary factors...

  • Effect of the food restriction diets on zinc concentration in the tissues of female Wistar rats (animal anorexia model). Wojciak, Rafal W. // Trace Elements & Electrolytes;2013 2nd Quarter, Vol. 30 Issue 2, p41 

    Aim: Although it is clear that zinc deficiency produces a specific and profound anorexia in experimental animals, the influence of food restriction on zinc management is less certain. The purpose of the present study was to assess the concentration of zinc in serum, erythrocytes, liver, kidney,...

  • Iron Status in Infants and Relation to Dietary Intake. Part 1: General and Developmental Aspects. Dube, Katharina; Kersting, Mathilde; Kalhoff, Hermann // Current Nutrition & Food Science;Nov2010, Vol. 6 Issue 4, p256 

    Iron deficiency is one of the leading nutritional problems worldwide, affecting an estimated total of about 2 billion individuals. Nearly 40% of children younger than 5 years and about 50% of pregnant women in developing countries are anaemic. However, iron deficiency is also common in women and...

  • THE USE OF GAMES IN HEALTH EDUCATION IN ORDER TO PREVENT IRON DEFICIENCY ANEMIA IN INFANCY: THE ROLE OF THE NURSE -- LITERATURE SYSTEMATIC REVIEW. Câmara, Marilia Cruz Gouveia; de Sá  Barreto, Ana Maria; de Sousa Medeiros, Ana Priscilla Soares; de Lucena, Itala Fernanda Albuquerque; de Moura, Jéssica Viviane Silva; Oliveira, Tamires de Farias // Journal of Nursing UFPE / Revista de Enfermagem UFPE;Aug2011, Vol. 5 Issue 6, p1280 

    Objective: to describe the importance of playing during the nursing actions in order to prevent anemia. Method: this is a descriptive review, which had undertaken a literature research of publications of the past ten years. Results: 118 items were found, of which thirteen were selected by...

  • Strategies for the Prevention and Treatment of Iron Deficiency during Pregnancy. Remacha, A.F. // Clinical Drug Investigation;2000 Supplement 1, Vol. 19 Issue 6, p29 

    Iron deficiency is the most frequent micronutrient deficiency in humans. It is especially prevalent in certain risk groups, which, because of their elevated requirements, include pregnant women and women of childbearing age. During pregnancy the parameters of iron metabolism are altered, and...

  • Plant Ferritin—A Source of Iron to Prevent Its Deficiency. Zielińska-Dawidziak, Magdalena // Nutrients;2015, Vol. 7 Issue 2, p1184 

    Iron deficiency anemia affects a significant part of the human population. Due to the unique properties of plant ferritin, food enrichment with ferritin iron seems to be a promising strategy to prevent this malnutrition problem. This protein captures huge amounts of iron ions inside the...

  • LIFE-CHANGING FISH. Klein, Andrew // Science World;9/21/2015, Vol. 72 Issue 2, p12 

    The article offers information on the Lucky Iron Fish that Canadian graduate student Christopher Charles has created to help combat iron deficiency which causes anemia in Cambodia.

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics