Double Outbreak of Measles in the Talaja Block of Bhavnagar District, Gujarat, India 2011: A Need for Improving the Vaccine Coverage and the Community Participation

December 2012
Journal of Clinical & Diagnostic Research;Dec2012, Vol. 6 Issue 10, p1713
Academic Journal
Background: Two outbreaks of measles were reported from an urban and a village area of Bhavnagar District, Gujarat, India in January and March 2011 respectively. Aim: The present study was conducted to investigate and to assess various epidemiological features which were associated with the measles outbreak. Settings and Design: The present study was designed as a cross sectional study, which was conducted in an urban and a rural area of the Talaja block of the Bhavnagar district of Gujarat, India from December 2010 to April 2011. Methods and Material: The suspected cases were detected through an active case finding in the community. We defined a case clinically by the WHO criteria as the occurrence of a febrile rash with or without cough, coryza and conjunctivitis in a resident of the Talaja-urban and the Gorkhi village of the Talaja block, in the period from 1st December 2010 to 30th April 2011. Blood samples from 10 case patients were collected for the IgM antibody detection. A community based, retrospective, cohort design was carried out to find the vaccine efficacy in the Gorkhi village. Statistical Analysis: We entered and analyzed the data by using an MS-Excel sheet. Results: This study identified 27 confirmed cases of measles in the urban area of Talaja and 78 cases in Gorkhi village. All the 105 case patients belonged to the age group of 3 months-15 years. According to their mothers' statements, out of the 105 measles cases in the two areas, 40 (38%) case patients were immunized. Ten sera from five case-patients each from both the areas were tested; all were found to be positive for the IgM/IgG antibodies by ELISA. Conclusions: The outbreaks occurred due to a poor community participation and the poor vaccine coverage levels.


Related Articles

  • Specific Anti Mumps Antibodies (IgG & IgM) in Cerebrospinal Fluid of Mumps Meningoencephalitic Children. Noorbakhsh, Samileh; Javahertrash, Naser; Tonekaboni, Hassan; Tabatabaei, Azardokht; Fatoorechi, Mohammad Ali // Acta Medica Iranica;2009, Vol. 47 Issue 3, p171 

    Mumps infection is endemic in Iran. Our objective was to evaluate the presence of anti mumps antibodies ( IgM & IgG) in cerebrospinal fluid in mumps meningoencephalitic children. A prospective/crosssectional study was performed in Tehran, Iran (2003 to 2004) and serum anti mumps antibodies (IgM)...

  • Incidence of rubella IgM antibodies in individuals with febrile rash illness attending clinics in Akwa Ibom State, Nigeria, 2006-2009. Enya, Bassey; Effiong, Moses Anietie; Moffat, Udo Sunde; Emem, Bassey // Health (1949-4998);Jun2011, Vol. 3 Issue 6, p362 

    Background: Rubella is an infectious disease of public health importance because infection acquired during early pregnancy often results in foetal abnormalities that are classified as congenital rubella syndrome (CRS). The burden of rubella infection in most developing countries is however not...

  • Immune response of healthy women to 2 different group B streptococcal type V capsular polysaccharide-protein conjugate vaccines. Baker, Carol J.; Paoletti, Lawrence C.; Rench, Marcia A.; Guttormsen, Hilde-Kari; Edwards, Morven S.; Kasper, Dennis L. // Journal of Infectious Diseases;3/15/2004, Vol. 189 Issue 6, p1103 

    Background: Infections caused by group B streptococcal (GBS) type V are increasingly common. Capsular polysaccharide (CPS)-protein conjugate GBS vaccines are immunogenic in healthy adults, but type V vaccines have not previously been tested.Methods: Thirty-five healthy,...

  • Group B Streptococcus Bacteremia Elicits β C Protein-Specific IgM and IgG in Humans. Pannaraj, Pia S.; Kelly, Joanna K.; Madoff, Lawrence C.; Rench, Marcia A.; Lachenauer, Catherine S.; Edwards, Morven S.; Baker, Carol J. // Journal of Infectious Diseases;2/1/2007, Vol. 195 Issue 3, p353 

    Group B Streptococcus (GBS) β C protein elicits protective antibodies in experimental animals, making β C protein an attractive component of a human GBS glycoconjugate vaccine. We determined whether natural exposure to β C protein elicits antibodies in humans. Geometric mean...

  • Quantification of IgM and IgA Anti-Pneumococcal Capsular Polysaccharides by a New ELISA Assay: a Valuable Diagnostic and Prognostic Tool for Common Variable Immunodeficiency. Cavaliere, F.; Milito, C.; Martini, H.; Schlesier, M.; Dräger, R.; Schütz, K.; Brunetti, G.; Pesce, A.; Thon, V.; Warnatz, K.; Quinti, I. // Journal of Clinical Immunology;May2013, Vol. 33 Issue 4, p838 

    Purpose: Existing ways of assessing CVID patients at risk of pulmonary infections are not universally accepted. The need to identify additional prognostic factors allowed us to evaluate the anti-polysaccharide IgA and IgM responses in 125 CVID patients immunized with the 23-valent pneumococcal...

  • Serologic evidence of human orthopoxvirus infections in Sierra Leone.  // BMC Research Notes;2011, Vol. 4 Issue 1, p465 

    The article reports on a serosurvey conducted to determine whether human exposure to orthopoxviruses continues to occur in eastern Sierra Leone, a country of 6 million inhabitants on the west coast of Africa. The researchers collected and tested sera from 1596 persons by IgG ELISA and a subset...

  • Dual infection of measles and rubella in Chitradurga district, Karnataka, India. Shaikh, N. J.; Raut, C. G.; Sinha, D. P.; Manjunath, M. J. // Indian Journal of Medical Microbiology;Jan2015, Vol. 33 Issue 1, p193 

    The article presents a study on dual infection of measles and rubella in Karnataka, India. Topics discussed include serum samples collected were processed for measles and rubella Immunoglobulin M (IgM) antibodies testing, test performed using IgM enzyme-linked immunosorbent assay (ELISA) kit...

  • Synthetic peptides as an antigenic base in an ELISA for laboratory diagnosis of schistosomiasis mansoni de Oliveira, Edward José; Kanamura, Hermínia Yohko; Takei, Kioko; Hirata, Rosario Dominguez Crespo; Valli, Luiz Carlos Pedrosa; Nguyen, Nga Yen; de Carvalho Rodrigues, Izabel; de Jesus, Amélia Ribeiro; Hirata, Mário Hiroyuki // Transactions of the Royal Society of Tropical Medicine & Hygiene;Apr2008, Vol. 102 Issue 4, p360 

    Summary: A pool of five synthetic peptides was used as an antigenic base in an ELISA (ELISA-Pp) for laboratory diagnosis of Schistosoma mansoni. Serum samples were obtained from individuals with acute (n =23) and chronic (n =30) schistosomiasis, with other parasitoses (n =39) or without...

  • Brucellosis and the Respiratory System. Pappas, Georgios; Bosilkovski, Mile; Akritidis, Nikolaos; Mastora, Maria; Krteva, Liliana; Tsianos, Epaminondas // Clinical Infectious Diseases;10/1/2003, Vol. 37 Issue 7, p95 

    Describes the involvement of the respiratory system in brucellosis in Balkan Peninsula. Accounts on the predominance of monocytic or lymphocytic infiltrates; Inhalation of the infectious aerosols particles; Use of enzyme-linked immunosorbent assay to detect immunoglobulin M antibodies.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics