TITLE

Vitamin D levels in Malawian infants from birth to 24 months

AUTHOR(S)
Amukele, Timothy K.; Soko, Dean; Katundu, Pauline; Kamanga, Melvin; Sun, Jin; Kumwenda, Newton I.; Taha, Taha E.
PUB. DATE
March 2013
SOURCE
Archives of Disease in Childhood;Mar2013, Vol. 98 Issue 3, p180
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
We measured longitudinal levels of vitamin D in unsupplemented Malawian infants at 0 (birth), 2, 12, 15, 18 and 24 months of age. Matched maternal plasma and breast milk vitamin D2 and D3 levels were also measured at delivery and 2 months postpartum. Vitamin D was measured using isotope-dilution liquid chromatography tandem-mass spectrometry. Vitamin D3 levels in children were 36% of adult levels at birth, 60% of adult levels at age 2 months, and at par with adult levels by 12 months of age. This adult-equivalent level is subsequently maintained through age 24 months and consisted of a 98% molar ratio of vitamin D3. Vitamin D levels in breast milk were below the limit of detection, 0.1 ng/ml. Breast milk of unsupplemented Malawian mothers is a poor source of vitamin D.
ACCESSION #
86924173

 

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