Onychomycosis Case Developing during Interferon Treatment

Tuna, Nazan; Teoman Erdem, Mustafa; Karabay, Oğuz
March 2013
Balkan Medical Journal;Mar2013, Vol. 30 Issue 1, p131
Academic Journal
The article discusses some of the side effects following the use of interferons (IFNs) that are used in the treatment of hepatitis B and hepatitis C infections. The cutaneous side effects include dermatitis, hyperpigmentation, malar erythema, prurigo, acantholytic dermatosis, eczema, diffuse hypertricosis, vitiligo and alopecia. The case of a 45-year-old male suffering from onychomycosis as a result of IFN side effect due to treatment for chronic hepatitis B for 10 years is highlighted.


Related Articles

  • Is this toenail condition threatening? Monroe, Joe R. // JAAPA: Journal of the American Academy of Physician Assistants (;Jul2012, Vol. 25 Issue 7, p16 

    The article presents a case study of a 42-year-old man presented for evaluarion of changes to his toenail that began 2 years ago. He was diagnosed with onychomyeosis and treatment with terbinafine 250 mg was started to be continued for 4 months and antifungal lotion for the nail was also...

  • Clinico‑Mycological Study of Dermatophyte Toenail Onychomycosis in New Delhi, India. Yadav, Pravesh; Singal, Archana; Pandhi, Deepika; Das, Shukla // Indian Journal of Dermatology;Mar/Apr2015, Vol. 60 Issue 2, p153 

    Introduction: There is a constant need to define the epidemiological and mycological characteristics of onychomycosis (OM) for optimal management strategies. Objectives: To define the epidemiological and mycological characteristics of patients with dermatophyte toenail OM in a tertiary care...

  • EVALUATION OF CLINICOMYCOLOGICAL ASPECTS OF ONYCHOMYCOSIS. Kaur, Ravinder; Kashyap, Bineeta; Makkar, Rati // Indian Journal of Dermatology;Oct-Dec2008, Vol. 53 Issue 4, p174 

    Background: Incidence of onychomycosis has increased tremendously in recent times. Relatively little work has been done on this problem in our country. Research in past has been concentrated mainly on superficial mycoses of the skin. Aim: It is a well-established fact that geographical...

  • Comparison of potassium hydroxide mount and mycological culture with histopathologic examination using periodic acid-Schiff staining of the nail clippings in the diagnosis of onychomycosis. Shenoy, M. Manjunath; Teerthanath, S.; Karnaker, Vimal K.; Girisha, B. S.; Prasad, M. S. Krishna; Pinto, Jerome // Indian Journal of Dermatology, Venereology & Leprology;May/Jun2008, Vol. 74 Issue 3, p226 

    Background: Onychomycosis is a common problem noticed in clinical practice. Currently available standard laboratory methods show inconsistent sensitivity; hence there is a need for newer methods of detection. Aims: This study involves comparison of standard laboratory tests in the diagnosis of...

  • Not only fever and palmoplantar vesicular eruption. Cuppari, Caterina; Manti, Sara; Arrigo, Teresa; Salpietro, Carmelo // Infection;Oct2014, Vol. 42 Issue 5, p947 

    The article focuses on nail matrix arrest that is caused due to various reasons including physiological stress, nutritional deficiencies and and systemic illnesses such as hand-foot-mouth disease (HFMD). HFMD is a possible cause of onychomadesis and it was first described in 2000 in five...

  • Idiopathic hepatitis B surface antibody seroreversion after pegylated interferon alpha-2a therapy. Tsynman, Donald N.; Rivera, Rene; Maliakkal, Benedict // Journal of Gastrointestinal & Liver Diseases;Mar2013, Vol. 22 Issue 1, p110 

    A letter to the editor is presented which discusses a case study of a 40-year-old male with idiopathic hepatitis B virus (HBV) who undergone treatment with pegylated interferon alpha-2a.

  • Interferon Alpha on Expression of hTERT mRNA in Peripheral Blood Mononuclear Cells of Patients with Chronic Hepatitis B. Chuan-wu Zhu; Ming Chen; Xiang-rong Luo; Hai-yan Wang; Li-hua Wang; Jian-hong Wu; Ming Li; Xue-hua Zhang; Wei Zhu; Jian-zhong Ye; Feng Qian // Clinical & Developmental Immunology;2011, p1 

    Cell division is closely related to telomerase activity (hTERT mRNA). Lower expression of lymphocitic hTERT mRNA may easily cause cell aging, which is not beneficial to maintaining a durable lymphocyte division. To date, there is no study to investigate IFNα therapy on hTERT mRNA expression...

  • What is the best method of diagnosing onychomycosis? Rea, Cathy; Greenawald, Mark H. // Journal of Family Practice;Dec2003, Vol. 52 Issue 12, p929 

    This study indicated that nail plate biopsy followed by periodic acid-Schiff staining is the most accurate method for diagnosing onychomycosis. The positive predictive value (PV+) of periodic acid-Schiff staining was equal to both potassium hydroxide (KOH) preparation and fungal culture, with a...

  • Onikomikoz Tanısında Kullanılan YÖntemlerin KarşılaÅŸtırılması. Ceren, Eylem; Ekmekci, Tuğba Rezan; Sakız, Damlanur; Köşlü, Adem; Bayraktar, Banu // Archives of the Turkish Dermatology & Venerology / Turkderm;2008, Vol. 42 Issue 3, p91 

    Background and Design: A potassium hydroxide (KOH) direct microscopic examination, histopathological investigation with periodic acid-Schiff (PAS) stain and fungal culture are common diagnostic methods in the diagnosis of onychomycosis. The purpose of this study was to compare these three...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics