TITLE

SureClick® (Darbepoetin alfa) can improve perceived satisfaction and competence for anemia treatment and increase self-administration in non-dialyzed patients with chronic kidney disease

AUTHOR(S)
Bonafont, Xavier; Romero, Ramón; Martínez, Isabel; del Pino, María D.; Gil, José M.; Aranda, Pedro; Roca, Ramón; Claverol, Joana; Cucala, Mercedes
PUB. DATE
March 2013
SOURCE
Nefrologia;2013, Vol. 33 Issue 2, p214
SOURCE TYPE
Periodical
DOC. TYPE
Article
ABSTRACT
Background and aims: SureClick® is a prefilled pen for administration of darbepoetin alfa (DA) that is readyto- use. We explored patient satisfaction with SureClick® compared with prefilled syringes (PFS). Methods: Multicenter, prospective, 6-months, observational study in non-dialyzed patients with chronic kidney disease (CKD) treated with DA in PFS who switched to SureClick® at baseline. Main outcomes were: change in Anemia Treatment Satisfaction Questionnaire (ATSQ-S), Perceived Competence for Anemia Scale (PCAS) and selfadministration rate. Results: We enrolled 132 patients with a mean(SD) age of 71.3 (14.6) years, 57.6% women. Mean(SD) ATSQ-S scores at baseline and final records were 25.5 (7.9) and 31.6 (4.9) (on a scale from 0 to 36 –maximum satisfaction-, mean change: 6.2, 95%CI: 4.6- 7.8, P<0.0001). The PCAS also increased significantly (4.3 (2.0) vs 5.6 (1.6), on a scale from 1 to 7 –maximum competence, P<0.0001). At baseline 47.7% of patients self-administered DA with PFS, vs 74.2% with SureClick® (P<0.001). No significant changes in hemoglobin were observed (11.4 (0.5) vs 11.6 (1.3) g/dl, P=0.193). Two patients (1.5%) had adverse reactions to SureClick® (pain on application). Conclusions: Our results suggest that the change from PFS to SureClick® could increase patient satisfaction and perceived competence in anemia management in non-dialyzed CKD patients, and could increase the self-administration rate, thereby reducing use of health resources.
ACCESSION #
87531162

 

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