TITLE

TB/HIV Co-Infection Profile and Impact of RNTCP and NACP Liaison in the Setting of Free Home Based Antiretroviral Therapy in a Rural Tertiary Teaching Hospital in India

AUTHOR(S)
Kundu, Susmita; Kanji, Dipankar; Dey, Atin; Ghoshal, A.G.; Mitra, Ritabrata; Misra, Swapnendu
PUB. DATE
June 2013
SOURCE
International Medical Journal;Jun2013, Vol. 20 Issue 3, p292
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background and Objective: Tuberculosis (TB) is the most common opportunistic infection (OI) among patients with HIV infection and causes significant morbidity and mortality. Our objective was to see prevalence and incidence of tuberculosis among patients with HIV on free highly active antiretroviral therapy (HAART) and impact of RNTCP & NACP linkage. Methods: All patients who are eligible for highly active antiretroviral therapy (HAART) were asked about past history of Tuberculosis, pulmonary or extra pulmonary with history of treatment received (DOTS/NonDOTS), screened for TB at baseline as well as during regular follow up (monthly or earlier, if necessary). Results: Out of total 384 clients, 156 (40.6%) suffered from TB, after infected with HIV. Majority of patients 87 (55.76%) suffered from TB < 2 years before initiation of HAART, more commonly with disseminated or sputum smear negative pulmonary TB. Good number of patients 13 (8.3%) were detected with active TB infection during screening for antiretroviral therapy (ART) eligibility. 32 (20.5%) cases were diagnosed with active TB in the post ART period during regular follow up. Those who suffered from TB after initiation ART they took regular antitubercular drugs (ATD) under Revised National Control Programme (RNTCP). Conclusion: TB is the most common opportunistic infection (OI) in our study population. Incidence of disseminated and sputum smear negative pulmonary TB is more common during advance stage of HIV infection. There is close liaison between NACP and RNTCP once patient is put on HAART. I/CV \kir\DT\C
ACCESSION #
89730159

 

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