TITLE

Community-acquired CTX-M-15-type ESBL-producing Escherichia coli meningitis: a case report and literature review

AUTHOR(S)
Elaldi, Nazif; Gozel, Mustafa G.; Kolayli, Fetiye; Engin, Aynur; Celik, Cem; Bakici, Mustafa Z.; Vahaboglu, Haluk
PUB. DATE
May 2013
SOURCE
Journal of Infection in Developing Countries;May2013, Vol. 7 Issue 5, p424
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
In this report, a case of community-acquired acute bacterial meningitis (CA-ABM) caused by CTX-M-15-producing Escherichia coli in an elderly male patient was presented in the light of literature. Cultures of cerebrospinal fluid, blood, ear discharge, and stool samples yielded CTX-M-15-producing E. coli in-vitro, which was resistant to the extended-spectrum cephalosporins and ciprofloxacin and susceptible to imipenem, meropenem and amikacin. Meningitis was treated with parenteral meropenem plus parenteral and intraventricular amikacin administration. Since bacterial meningitis is a life-threatening infection, empiric antibiotic therapy with carbapenem can be started before the culture results are obtained, mainly in areas where the ESBL epidemiology is well known.
ACCESSION #
90361871

 

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