TITLE

Developing stem cells -- the hard way

AUTHOR(S)
Lougheed, Tim
PUB. DATE
October 2013
SOURCE
CMAJ: Canadian Medical Association Journal;10/1/2013, Vol. 185 Issue 14, pE661
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article reports on the use of the somatic cell nuclear transfer method by U.S. researchers to turn human skin cells into embryonic stem cells. The objective of the team led by researcher Shoukhrat Mitalipov was to identify a stem cell line for tackling injury, disease and genetic disorders that would lead to personalized therapy. It is noted that the method is illegal in Canada.
ACCESSION #
90519920

 

Related Articles

  • Success Reported in Cloning Human Embryonic Stem Cells. Breindl, Anette; Moran, Nuala // BioWorld International;5/22/2013, Vol. 18 Issue 21, p3 

    The article discusses research about the cloning of human embryonic stem cells. It references a study from Shoukhrat Mitalipov from Oregon Health & Science University and colleagues published in "Cell." The researchers refined the somatic cell nuclear transfer (SCNT) process to produce SCNT...

  • Yamanaka factors critically regulate the developmental signaling network in mouse embryonic stem cells. Liu, Xiaosong; Huang, Jinyan; Chen, Taotao; Wang, Ying; Xin, Shunmei; Li, Jian; Pei, Gang; Kang, Jiuhong // Cell Research;Dec2008, Vol. 18 Issue 12, p1177 

    Yamanaka factors (Oct3/4, Sox2, Klf4, c-Myc) are highly expressed in embryonic stem (ES) cells, and their over-expression can induce pluripotency in both mouse and human somatic cells, indicating that these factors regulate the developmental signaling network necessary for ES cell pluripotency....

  • Plans for stem cell research could be blocked. Dickson, David // Nature Medicine;Dec2000, Vol. 6 Issue 12, p1303 

    Reports on the possibility that British researchers' plans to carry out embryo research using somatic cell nuclear transfer techniques could be blocked by the British Parliament. Defeat in October 2000 of a private members bill introduced into the House of Commons that would allow such research...

  • Inducing definitive hematopoiesis in a dish. Yoder, Mervin C // Nature Biotechnology;Jun2014, Vol. 32 Issue 6, p539 

    The article discusses research into inducing hematopoiesis in the laboratory and references a study by researchers C.M. Sturgeon, A. Ditad and G. Awong published in the "Nature Biotechnology" journal in 2014. Topics highlighted include a background on hematopoiesis researchers' attempts to...

  • Point: The Potential of Stem Cell Research. Pearson, John // Points of View: Stem Cell Research;12/31/2017, p5 

    This article presents an argument on the potential of stem cell research. Therapeutic treatments involving stem cells show tremendous potential for the treatment of complex diseases related to genetic disorders that now afflict millions of people. Federal funding for such research should be...

  • iPS and ES Cells: Do Both Roads Lead to Rome? Ng, Valerie Y.; Choo, Andre B. H. // Open Stem Cell Journal;2010 Special Issue, p8 

    The seminal report from Takahashi and Yamanka in 2006 describing the reprogramming of somatic cells to induced pluripotent stem (iPS) cells [1] marked the beginning of a new field of research, resulting in hundreds of publications in a short 3 years. Among other things, the promise of iPS cells...

  • Reduce, reuse, reprogram. Zwaka, Thomas P. // Nature Methods;Jan2010, Vol. 7 Issue 1, p39 

    The article comments on two papers on epigenetic reprogramming in mouse for the generation of induced pluripotent stem cells (iPSCs) from the embryonic stem cells (ESCs) for studying multiple cell types, published within the issue. It is stated that these papers solve the problem of secondary...

  • UK Research Groups Get OK for Human/Animal Cloned Embryos. Moran, Nuala // BioWorld International;1/23/2008, Vol. 13 Issue 4, p1 

    The article reports on the approval given to two British research teams to create human/animal cloned embryos for use in embryonic stem cell research. The decision of the Human Fertilization and Embryology Authority (HFEA) will allow researchers to use nucleated animal oocytes as the vehicle for...

  • Subtelomeric hotspots of aberrant 5-hydroxymethylcytosine-mediated epigenetic modifications during reprogramming to pluripotency. Wang, Tao; Wu, Hao; Li, Yujing; Szulwach, Keith E.; Lin, Li; Li, Xuekun; Chen, I-Ping; Goldlust, Ian S.; Chamberlain, Stormy J.; Dodd, Ann; Gong, He; Ananiev, Gene; Han, Ji Woong; Yoon, Young-sup; Katharine Rudd, M.; Yu, Miao; Song, Chun-Xiao; He, Chuan; Chang, Qiang; Warren, Stephen T. // Nature Cell Biology;Jun2013, Vol. 15 Issue 6, p700 

    Mammalian somatic cells can be directly reprogrammed into induced pluripotent stem cells (iPSCs) by introducing defined sets of transcription factors. Somatic cell reprogramming involves epigenomic reconfiguration, conferring iPSCs with characteristics similar to embryonic stem cells (ESCs)....

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics