TITLE

The Impact of HIV on the Usefulness of Sputum Smears for the Diagnosis of Tuberculosis

AUTHOR(S)
Long, Richard; Scalcini, Marcella; Manfreda, Jure; Jean-Baptiste, Michel; Herchfield, Earl
PUB. DATE
October 1991
SOURCE
American Journal of Public Health;Oct91, Vol. 81 Issue 10, p1326
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
In a developing country, 289 patients were examined for active pulmonary mycobacterial disease (sputum smear and culture) and HIV infection (serology) to compare the sensitivity and positive predictive value of sputum smears for diagnosing pulmonary tuberculosis in patients with and without antibodies to HIV. Seventy-nine percent of HIV-seronegative vs 66% of HIV-seropositive patients with positive cultures for Mycobacterium tuberculosis were smear positive (P < .05), and a positive sputum smear predicted the presence of M. tuberculosis in 90% of HIV seronegative vs 80% of HIV seropositive patients (P < .05). In our opinion, HIV did not significantly compromise the diagnostic utility of the sputum smear.
ACCESSION #
9112090824

 

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