TITLE

La obesidad infantil, un problema de salud multisistémico

AUTHOR(S)
Castro, Ana María; Toledo-Rojas, Andrea Alejandra; Macedo-De La Concha, Lilia E.; Inclán-Rubio, Virginia
PUB. DATE
January 2012
SOURCE
Revista Medica del Hospital General de Mexico;ene-mar2012, Vol. 75 Issue 1, p41
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Overweight and obesity, are one of the most important public health problems in México. Obesity childhood is a chronic disease with a multifactorial origin. Is characterized by excess of fat in the body and occurs when the child is overweight more than 20% of its ideal weight. Obesity is associated with a state of low-level inflammation, mediated by adipocytokines, which occurs mainly in visceral fat and that leads the child to submit changes such as type 2 diabetes mellitus, metabolic syndrome, polycystic ovarian disease and cardiovascular disease, among other. This occurs because the adipose visceral tissue functions as an endocrine organ. As responsible for obesity are genetic, socioeconomic, cultural and psychological factors. This article looks at the involvement of neuroendocrine and immune systems in the generation and maintenance of overweight and obesity, and the main pathways and mechanisms leading to these processes. Also discusses some factors participated in inflammation and metabolic disease and inflammation-obesity association. Understanding the cellular and hormonal mechanisms involved in the generation and evolution of obesity, will address the problem and thereby reduce morbidity and mortality of this disease.
ACCESSION #
91514165

 

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