Stem cells: A reprogrammable rodent

Da Silva, Kevin
November 2013
Nature Medicine;Nov2013, Vol. 19 Issue 11, p1376
Academic Journal
The article reports on a study, conducted by Manuel Serrano and his colleagues and published in the journal "Nature," which demonstrates the in vivo reprogramming of somatic cells into induced pluripotent stem (iPS) cells using a mouse model through administration of doxycycline.


Related Articles

  • Retraction. Smith, Austin // Nature;7/3/2014, Vol. 511 Issue 7507, p40 

    A retraction to the article "Stimulus-triggered fate conversion of somatic cells into pluripotency" that was published in a January 2014 issue is presented.

  • Corrigendum: Deterministic direct reprogramming of somatic cells to pluripotency. Rais, Yoach; Zviran, Asaf; Geula, Shay; Gafni, Ohad; Chomsky, Elad; Viukov, Sergey; Mansour, Abed AlFatah; Caspi, Inbal; Krupalnik, Vladislav; Zerbib, Mirie; Maza, Itay; Mor, Nofar; Baran, Dror; Weinberger, Leehee; Jaitin, Diego A.; Lara-Astiaso, David; Blecher-Gonen, Ronnie; Shipony, Zohar; Mukamel, Zohar; Hagai, Tzachi // Nature;4/30/2015, Vol. 520 Issue 7549, p710 

    A correction to the article "Deterministic direct reprogramming of somatic cells to pluripotency" that was published in a previous issue.

  • Generation of hircine-induced pluripotent stem cells by somatic cell reprogramming. JiangtaoRen; Yongjun Pak; Lixiazi He; Lei Qian; Yijun Gu; Hui Li; Lingjun Rao; Jing Liao; Chun Cui; Xun Xu; Jinqiu Zhou; Hakchol Ri; Lei Xiao // Cell Research;May2011, Vol. 21 Issue 5, p849 

    A letter to the editor is presented, related to the generation of hircine-induced pluripotent stem cells, with the help of somatic cell reprogramming.

  • Retraction: Stimulus-triggered fate conversion of somatic cells into pluripotency. Obokata, Haruko; Wakayama, Teruhiko; Sasai, Yoshiki; Kojima, Koji; Vacanti, Martin P.; Niwa, Hitoshi; Yamato, Masayuki; Vacanti, Charles A. // Nature;7/3/2014, Vol. 511 Issue 7507, p112 

    A retraction to the article "Stimulus-triggered fate conversion of somatic cells into pluripotency" that was published in the January 30, 2014 issue is presented.

  • Stem cells: Cloning advance calls for careful regulation. Hyun, Insoo; Tesar, Paul // Nature;10/6/2011, Vol. 478 Issue 7367, p36 

    The article reports a study on human pluripotent stem cells with the use of somatic cells and oocytes wherein it explores fertilized embryos without ethical concerns.

  • The fate of cell reprogramming. Karagiannis, Peter; Yamanaka, Shinya // Nature Methods;Oct2014, Vol. 11 Issue 10, p1006 

    The article presents the authors' opinion on cell reprogramming and the ability to convert somatic cells to induced pluripotent stem cells which has potential to further understanding of development and disease mechanisms, as well as for cellular therapy. The authors say researchers must expand...

  • Use of Induced Pluripotent Stem Cells in Dermatological Research. Dinella, Jason; Koster, Maranke I; Koch, Peter J // Journal of Investigative Dermatology;Aug2014, Vol. 134 Issue 8, pe23 

    The article discusses a study regarding the potential of induced pluripotent stem cells (iPSCs) to differentiate into any of the body's cell type such as somatic cells. Topics include the advantages, characterization, and limitations of iPSCs, the evaluation of genes with pluripotency, and the...

  • Stem cells: Multiple routes to pluripotency. Baumann, Kim // Nature Reviews Molecular Cell Biology;Jan2015, Vol. 16 Issue 1, p1 

    The article discusses the different routes of reprogramming somatic cells into pluripotent stem cells. It cites various studies that provide a comprehensive analysis of the molecular changes in induced pluripotent stem cells in multiple states. It reveals the possibility of creating artificial...

  • Stem cells: Multiple routes to pluripotency. Baumann, Kim // Nature Reviews Genetics;Feb2015, Vol. 16 Issue 2, p67 

    The article highlights a study reporting extensive transcriptomic, epigenomic and proteomic analyses of reprogramming, revealing the existence of several reprogramming routes and showing that induced pluripotent stem (iPS) cells exist in multiple unique cell states. The studies provide a...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics