TITLE

Infertility, Pregnancy Loss and Adverse Birth Outcomes in Relation to Maternal Secondhand Tobacco Smoke Exposure

AUTHOR(S)

Meeker, John D.; Benedict, Merle D.

PUB. DATE

February 2013

SOURCE

Current Women's Health Reviews;Feb2013, Vol. 9 Issue 1, p41

SOURCE TYPE

Academic Journal

DOC. TYPE

Article

ABSTRACT

A substantial proportion of the etiology involved in female infertility and adverse pregnancy outcomes remainsidiopathic. Recent scientific research has suggested a role for environmental factors in these conditions. Secondhandtobacco smoke (STS) contains a number of known or suspected reproductive toxins, and human exposure to STS isprevalent worldwide. Robust evidence exists for the toxic effects of active smoking on fertility and pregnancy, but studiesof passive exposure are much more limited in number. While the association between maternal STS exposure anddeclined birth weight has been fairly well-documented, only recently have epidemiologic studies begun to providesuggestive evidence for delayed conception, altered menstrual cycling, early pregnancy loss (e.g. spontaneous abortion),preterm delivery, and congenital malformations in relation to STS exposure. There is also new evidence thatdevelopmental exposures to tobacco smoke may be associated with reproductive effects in adulthood. To date, moststudies have estimated maternal STS exposure through self-report even though exposure biomarkers are less prone toerror and recall bias. In addition to utilizing biomarkers of STS exposure, future studies should aim to identify vitalwindows of STS exposure, important environmental co-exposures, individual susceptibility factors, and specific STSconstituents associated with female infertility and adverse pregnancy outcomes. The role of paternal exposures/factorsshould also be investigated.

ACCESSION #

92631214

 

Related Articles

• Infertility, Pregnancy Loss and Adverse Birth Outcomes in Relation to Maternal Secondhand Tobacco Smoke Exposure. Meeker, John D.; Benedict, Merle D. // Current Women's Health Reviews;Nov2012, Vol. 8 Issue 4, p41 

  A substantial proportion of the etiology involved in female infertility and adverse pregnancy outcomes remainsidiopathic. Recent scientific research has suggested a role for environmental factors in these conditions. Secondhandtobacco smoke (STS) contains a number of known or suspected...

• Associations of lifetime active and passive smoking with spontaneous abortion, stillbirth and tubal ectopic pregnancy: a cross-sectional analysis of historical data from the Women's Health Initiative. Hyland, Andrew; Piazza, Kenneth M.; Hovey, Kathleen M.; Ockene, Judith K.; Andrews, Christopher A.; Rivard, Cheryl; Wactawski-Wende, Jean // Tobacco Control;Jul2015, Vol. 24 Issue 4, p328 

  Objective To examine the associations between tobacco exposure and adverse pregnancy outcomes using quantitative measures of lifetime active smoking and secondhand smoke (SHS) exposure. Methods Historical reproductive data on 80 762 women who participated in the Women's Health Initiative...

• Diffuse uterine leiomyomatosis in patient with successful pregnancy following new surgical management. Otsubo, Yasuo; Nishida, Masato; Arai, Yuko; Ichikawa, Ryota; Sakanaka, Miyako // Archives of Gynecology & Obstetrics;Oct2014, Vol. 290 Issue 4, p815 

  Diffuse uterine leiomyomatosis is associated with significant infertility and miscarriage complications. Appropriate diagnosis and therapy is essential. A 33-year-old woman was referred to our hospital because of GnRH analogue treatment-resistant multiple myomas and infertility. Following new...

• Hysterosalpingographic features of cervical abnormalities: acquired structural anomalies. ZAFARANI, F.; AHMADI, F.; SHAHRZAD, G. // British Journal of Radiology;Aug2015, Vol. 88 Issue 1052, p1 

  Cervical abnormalities may be congenital or acquired. Congenital cervical structural anomalies are relatively uncommon, whereas acquired cervical abnormalities are commonly seen in gynaecology clinics. Acquired abnormalities of the cervix can cause cervical factor infertility and recurrent...

• The Beat. Dooley, Erin E. // Environmental Health Perspectives;Jan2003, Vol. 111 Issue 1, pA21 

  Presents environmental news. Higher risk of miscarriage and of giving birth to babies with low birth weights by 62 percent of pregnant women in Japan due to environmental tobacco smoke exposure; Agreement between four of the largest chlorofluorocarbon (CFC) manufacturers in India to use cleaner...

• Safety of modern treatment for cervical pre-cancer. Strander, Björn; Adolfsson, Jan // BMJ: British Medical Journal;11/8/2014, Vol. 349 Issue 7982, pg6611 

  The authors discuss safety issues in the modern treatment for cervical pre-cancer, particularly cervical intraepithelial neoplasia (CIN). They present two studies that analyzed the possible harms to human reproduction of the CIN treatments, particularly on fertility. Also examined is the...

• Increasing the risk of spontaneous abortion and major malformations in newborns following use of serotonin reuptake inhibitors during pregnancy: A systematic review and updated meta-analysis. Nikfar, Shekoufeh; Rahimi, Roja; Hendoiee, Narjes; Abdollahi, Mohammad // DARU;2012, Vol. 20, p1 

  Selective serotonin reuptake inhibitors (SSRIs) are the most frequently used antidepressants during pregnancy. There are conflicting results about their influence on pregnancy outcomes. The goal of this study was to update our previous meta-analysis about pregnancy outcomes following exposure to...

• Antibiotic Tied to Higher Risk of Miscarriage. Smith, Michael // Inside Childbirth Education;Jan2013, p6 

  The article presents a study focused on analyzing the use of the antibiotic clarithromycin in first three months of pregnancy, published in the online periodical "Plos One." According to research, clarithromycin increases risk of miscarriage in first trimester whereas it is safe if consumed in...

• Study: Caffeine-Miscarriage Link.  // FDA Consumer;Mar/Apr2001, Vol. 35 Issue 2, p6 

  Focuses on a study on the association of miscarriage with caffeine consumption in Sweden and the United States. Factors increasing the risk of miscarriage; Reasons for the aversion of pregnant women to coffee; Information on caffeine.

Read the Article