Treatment of Obesity: An Overview

Fabricatore, Anthony N.; Wadden, Thomas A.
March 2003
Clinical Diabetes;Spring2003, Vol. 21 Issue 2, p67
Academic Journal
The article reviews approaches to the treatment of obesity and suggests its prevention. To be overweight in the United States is very common. More than 3,200 overweight individuals with impaired glucose tolerance (IGT) were randomly assigned to one of three conditions which are placebo, metformin or a lifestyle intervention designed to induce a loss of initial weight and to increase physical activity to greater than 150 minutes per week. The Diabetes Prevention Program clearly showed that weight loss and increased physical activity can prevent the development of type 2 diabetes. A follow-up trial, Action for Health in Diabetes investigates whether modest weight loss and increased physical activity can reduce the incidence of fatal and nonfatal heart attack and stroke in overweight individuals who already have type 2 diabetes.


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