TITLE

Gallstone disease in severely obese children participating in a lifestyle intervention program: incidence and risk factors

AUTHOR(S)
Heida, A; Koot, B G P; vd Baan-Slootweg, O H; Pels Rijcken, T H; Seidell, J C; Makkes, S; Jansen, P L M; Benninga, M A
PUB. DATE
July 2014
SOURCE
International Journal of Obesity;Jul2014, Vol. 38 Issue 7, p950
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Introduction:Cholelithiasis is increasingly encountered in childhood and adolescence due to the rise in obesity. As in adults, weight loss is presumed to be an important risk factor for cholelithiasis in children, but this has not been studied.Methods:In a prospective observational cohort study we evaluated the presence of gallstones in 288 severely obese children and adolescents (mean age 14.1±2.4 years, body mass index (BMI) z-score 3.39±0.37) before and after participating in a 6-month lifestyle intervention program.Results:During the lifestyle intervention, 17/288 children (5.9%) developed gallstones. Gallstones were only observed in those losing >10% of initial body weight and the prevalence was highest in those losing >25% of weight. In multivariate analysis change in BMI z-score (odds ratio (OR) 3.26 (per 0.5 s.d. decrease); 95% CI:1.60-6.65) and baseline BMI z-score (OR 2.32 (per 0.5 s.d.); 95% CI: 1.16-4.70) were independently correlated with the development of gallstones. Sex, family history, OAC use, puberty and biochemistry were not predictive in this cohort. During post-treatment follow-up (range 0.4-7.8 years) cholecystectomy was performed in 22% of those with cholelithiasis. No serious complications due to gallstones occurred.Conclusion:The risk of developing gallstones in obese children and adolescents during a lifestyle intervention is limited and mainly related to the degree of weight loss and initial body weight.
ACCESSION #
96939589

 

Related Articles

  • Hey, Dad! McCord, Holly; McVeigh, Gloria // Prevention;Jun2003, Vol. 55 Issue 6, p58 

    Chilling research shows that being obese (at least 30 to 40 lb overweight) at age 30 can cost a guy up to 6 years of life. If you and your kids improve your eating and exercise habits, you'll both live longer. For Father's Day, vow to stop the insanity. Eating as a family means fewer fatty...

  • I'M SICK OF BEING BIG. Tan, Michelle // People;6/22/2009, Vol. 71 Issue 24, p98 

    The article presents an account of Georgia Davis, an overweight 15-year-old girl who left her family to attend a weight loss boarding school located in Brevard, North Carolina. A periodic account of Davis' activities during her nine-month stay at the camp where she managed to lose 202 pounds...

  • Overweight and obesity in children and adolescents: The South African problem. Rossouw, Hermanus A.; Grant, Catharina C.; Viljoen, Margaretha // South African Journal of Science;May/Jun2012, Vol. 108 Issue 5/6, p1 

    Overweight and obesity in children and adolescents are on the increase worldwide. Overweight and obesity increase the risk for the development of non-communicable diseases during childhood and adolescence, and predispose the individual to the development of overweight, obesity, cardiovascular...

  • Complications of obesity in children and adolescents. Daniels, S. R. // International Journal of Obesity;Apr2009 Supplement 1, Vol. 33, pS60 

    The increasing prevalence and severity of obesity in children and adolescents has provided greater emphasis on the wide variety of comorbid conditions and complications that can be experienced as a consequence of obesity. These complications can occur both in the short term and in the long term....

  • OPINION: CHILD OBESITY A 'PANDEMIC OF THE NEW MILLENNIUM'. Gately, Paul // Practice Nurse;Oct2008 Nutrition for Nurses, p06 

    The author offers his views on child obesity in Great Britain. According to the author, if children are given guidance on what to eat and how to exercise the cycle of overweight and obesity can be reversed. The author offers information on a specialist weight loss programme he set up for eight...

  • The metabolic parameters of obese children and the role of hyperinsulinism on weight loss. Alikasifoglu, A.; Yordam, N. // European Journal of Pediatrics;1999, Vol. 158 Issue 3, p269 

    Presents a study which investigated the metabolic parameters in obese children and the relationship between the plasma level of insulin and the success of weight reduction after weight loss treatment. Methodology; Results and discussion.

  • Evidence based management of childhood obesity. Edmunds, Laurel; Waters, Elizabeth; Elliott, Elizabeth J // BMJ: British Medical Journal (International Edition);10/20/2001, Vol. 323 Issue 7318, p916 

    Presents a hypothetical medical case of child who is very overweight and whose parents are looking for help. Prevention as a successful strategy to prevent obesity; Evaluation of weight status in children; Evidence based approach to seeking a treatment; Prevalence of overweight and obesity;...

  • Pharmacotherapy of Childhood Obesity. Freemark, Michael // Diabetes Care;Feb2007, Vol. 30 Issue 2, p395 

    The article presents an analysis of the benefits of lifestyle intervention and pharmacotherapy to the treatment of obesity in adults and children. It cites the role of biological factors in the difficulty of losing weight. Several placebo-controlled studies performed in obese adults showed that...

  • Trends in Weight Abnormality of School Children and Adolescents in Nigeria. Chinedu, Shalom Nwodo; Eboji, Okwuchukwu K.; Emiloju, Opeyemi C. // Journal of Medical Sciences;2012, Vol. 12 Issue 7, p239 

    No abstract available.

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics