TITLE

Patient Adherence To HAART Regimens: Challenges For Physician Assistants And Health Care Providers

AUTHOR(S)
Day, Marvin
PUB. DATE
January 2003
SOURCE
Internet Journal of Academic Physician Assistants;2003, Vol. 3 Issue 1, p42
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Patients often adhere incompletely and inadequately to highly active antiretroviral therapy (HAART) regimens used in the treatment of HIV infection. This permits the emergence of HIV variants that are resistant to current treatment. The physician assistant often assumes the responsibility for explaining to the patient the importance of adhering strictly to the regimen and for collaborating with the patient to overcome any problems. This report summarizes the major reasons for poor patient adherence regimen complexity, poor tolerability, and metabolic side effects and provides patient-friendly approaches that can be adopted in the context of the office visit to increase patients level of adherence to these challenging regimens.
ACCESSION #
9860540

 

Related Articles

  • The Safety and Efficacy of Enfuvirtide Therapy for HIV Infection in Patients with Hemophilia: A Case Series. Polizzotto, Mark N.; Street, Alison M.; Wright, Edwina // Clinical Infectious Diseases;8/15/2007, Vol. 45 Issue 4, pe39 

    The treatment of patients with human immmunodeficiency virus (HIV) infection and hemophilia involves unique challenges that may be addressed with novel antiretroviral classes. We describe the safety and efficacy of enfuvirtide therapy in 4 patients with severe hemophilia A. Although local skin...

  • Oral Glucose Loading for Detection of Mitochondrial Toxicity During HAART in HIV-Infected Patients. Ter Hofstede, Hadewych J. M.; Borm, George F.; Koopmans, Peter P. // Current HIV Research;Oct2007, Vol. 5 Issue 4, p389 

    Nucleoside reverse transcriptase inhibitors used in antiretroviral therapy may cause mitochondrial toxicity. Mitochondrial dysfunction leads to disturbance of the glucose metabolism, resulting in an accumulation of L-lactate. We tested the hypothesis that an oral glucose tolerance test (OGTT)...

  • Gynaecomastia associated with saquinavir therapy. Donovan, Basil; Bodsworth, Neil J.; Mulhall, Brian P.; Allen, Debbie // International Journal of STD & AIDS;Jan1999, Vol. 10 Issue 1, p49 

    Gynaecomastia has been reported in an HIV-1- infected man treated with a triple antiviral regimen including indinavir1. We describe 4 cases of men with gynaecomastia associated with saquinavir (hard gel capsule) therapy who denied taking any hormonal supplements or opiates.

  • Impact of Indinavir on the Quality of Life in Patients with Advanced HIV Infection Treated with Zidovudine and Lamivudine. Coplan, Paul M.; Cook, John R.; Carides, George W.; Heyse, Joseph F.; Wu, Albert W.; Hammer, Scott M.; Nguyen, Bach-Yen; Meibohm, Anne R.; DiNubile, Mark J. // Clinical Infectious Diseases;8/1/2004, Vol. 39 Issue 3, p426 

    Objective. in AIDS Clinical Trial Group (ACTG) study 320, triple-combination antiretroviral therapy including indinavir significantly slowed progression to acquired immunodeficiency syndrome or death, compared with treatment with dual nucleoside reverse-transcriptase inhibitors (NRTIs) alone, in...

  • Effect of Maintaining Highly Active Antiretroviral Therapy on AIDS Events among Patients with Late-Stage HIV Infection and Inadequate Response to Therapy. Gandhi, Tejal; Wei Wei; Amin, Kamal; Kazanjian, Powel // Clinical Infectious Diseases;3/15/2006, Vol. 42 Issue 6, p878 

    Background. We evaluated the effect of maintaining highly active antiretroviral therapy (HAART) on the development of new acquired immunodeficiency syndrome (AIDS)-related events in patients with late-stage human immunodeficiency virus (HIV) infection who had suboptimal CD4+ cell count and viral...

  • Five-Year Outcomes of the China National Free Antiretroviral Treatment Program.  // Annals of Internal Medicine;8/18/2009, Vol. 151 Issue 4, pI-42 

    The article presents a study on the rate of recovery of patients in the National Free Antiretroviral Treatment Program in China after five years. It notes that 48,785 patients with HIV were enrolled in the program under the highly active antiretroviral therapy. It mentions that after 6 months of...

  • Hope and hype.  // Network Magazine of the Canadian Women's Health Network;Winter1998/1999, Vol. 2 Issue 1, p3 

    Relates how the author decided to go on combination therapy to combat HIV-related symptoms. Author's initial refusal to take any AIDS drugs; Details of how the author reached the decision to try a combination of AIDS drugs; Author's daily medication routine; Effects of the combination therapy.

  • The risk of AIDS-defining events is decreasing over time in the German HIV-1 Seroconverter Cohort. Altmann, Mathias; an der Heiden, Matthias; Scheufele, Ramona; Hartmann, Katrin; Houareau, Claudia; Bartmeyer, Barbara; Hamouda, Osamah // BMC Infectious Diseases;2012, Vol. 12 Issue 1, p94 

    Background: With ageing of the HIV-infected population, long-term exposure to treatment, varying adherence, emerging resistance and complications to therapies, effectiveness of Highly Active Antiretroviral Therapy (HAART) needs to be monitored continuously at the population level. The German...

  • Oral Lesions of HIV Disease and HAART in Industrialized Countries. Hodgson, T. A.; Greenspan, D.; Greenspan, J. S. // Advances in Dental Research;Apr2006, Vol. 19 Issue 1, p57 

    The epidemiology of HIV-related oral disease in industrialized nations has evolved following the initial manifestations described in 1982. Studies from both the Americas and Europe report a decreased frequency of HIV-related oral manifestations of 10-50% following the introduction of HAART...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics