TITLE

Implantation Rates after Two and Five Days of Embryo Culture: A Comparative Study

AUTHOR(S)
Kaur, Prabhleen; Swarankar, M. L.; Maheshwari, Manju; Sharma, Seema
PUB. DATE
January 2014
SOURCE
JK Science;Jan-Mar2014, Vol. 16 Issue 1, p7
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The aim of our study was to compare the Implantation rates of embryos transferred after two and five days of culture. A Randomized, prospective study was conducted in Infertility clinic, Department of Obstetrics & Gynecology,Mahatma Gandhi Hospital, Jaipur on 300 patients aged 25-40 years undergoing in-vitro fertilization (IVF)/ intra-cytoplasmic sperm injection (ICSI) cycle from May 2010-April 2011. When three or more Grade-I embryos were observed on day 2 of culture, patients were divided randomly into two study groups, day 3 transfer group and blastocyst transfer group or day 5 transfer group having 150 patients each. IVF outcome in terms of Implantation rate was compared between the groups. The results were analyzed using proportions, standard deviation and chi-square test.Both the groups were similar for age, indication and number of embryos transferred. Embryo transfers on day 5 resulted in significantly higher ongoing pregnancy and implantation rates as compared with day 3 embryo transfers(44% and 35.17% versus 29.33% and 21.35%, respectively)(P< 0.001). No significant difference was found in terms of multiple gestations in both the groups. Embryo transfers on day 5 of culture give significantly higher chance of ongoing pregnancy and implantation rates per cycle and per transfer than day 3 transfers.
ACCESSION #
99092347

 

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