Incidence of Tuberculosis during Highly Active Antiretroviral Therapy in High-Income and Low-Income Countries

Lawn, Stephen D.; Wood, Robin
December 2005
Clinical Infectious Diseases;12/15/2005, Vol. 41 Issue 12, p1783
Academic Journal
The article presents the author's comments on the incidence of Tuberculosis during highly active antiretroviral therapy in high-income and low-income countries. Highly active antiretroviral therapy (HAART) has revolutionized the care of HIV-infected individuals, causing major reductions in HIV-associated morbidity and mortality. In contrast, however, it is emerging that patients receiving HAART retain a chronically heightened risk of disease due to other, more virulent pathogens, such as tuberculosis (TB) and invasive pneumococcal disease. In conclusion, despite major reductions in TB incidence among individuals receiving HAART, TB risk remains elevated among those receiving treatment in both high- and low-income countries.


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