Obesity in children with different risk factors for obstructive sleep apnea: a community-based study

Su, Miao-Shang; Zhang, Hai-Lin; Cai, Xiao-Hong; Lin, Ying; Liu, Pei-Ning; Zhang, Yuan-Bo; Hu, Wen-Zhen; Li, Chang-Chong; Xiao, Yan-Feng
February 2016
European Journal of Pediatrics;Feb2016, Vol. 175 Issue 2, p211
Academic Journal
journal article
Unlabelled: This study investigated the association between obesity and obstructive sleep apnea (OSA) in preschool and school-age children. Parents of obese and randomly chosen normal weight children completed a questionnaire on sleep-related symptoms, demography, family, and medical history. All subjects were invited to undergo polysomnography (PSG). OSA cases were defined as obstructive apnea hypopnea index (OAHI) ≥1. A total of 5930 children were studied with 9.5% obese (11.9% boys/6.1% girls), 205/2680 preschool and 360/3250 school children. There were 1030 children (535 obese/495 normal weight) who underwent PSG. OSA was higher in obese children and obese school children had higher OAHI, arousal index, and shorter total sleep time. However, there was no positive correlation between OSA and body mass index (BMI). The main risk factors for OSA in preschool children were adenotonsillar hypertrophy and recurrent respiratory tract infection. The main cause for OSA in school children was a history of parental snoring and obesity. Mallampati scores and sleep-related symptoms were found to be associated with OSA in both preschool and school children.Conclusion: We demonstrated differential risk factors for OSA in obese children, which suggest that a different mechanism may be involved in OSA development in preschool and school-age children.What Is Known: Various risk factors have been reported in obese children with OSA owing to the different age and different study design. Obese children have a higher prevalence and severity of obstructive sleep apnea (OSA). OSA risk factors in obese children are affected by different ages and study designs.What Is New: A differential prevalence and risk factors for obese preschool and school-age children with OSA has been demonstrated.


Related Articles

  • Weight Loss and Sleep-Disordered Breathing in Childhood Obesity: Effects on Inflammation and Uric Acid. Van Hoorenbeeck, Kim; Franckx, Hilde; Debode, Patrick; Aerts, Petra; Wouters, Kristien; Ramet, Jose; Van Gaal, Luc F.; Desager, Kristine N.; De Backer, Wilfried A.; Verhulst, Stijn L. // Obesity (19307381);Jan2012, Vol. 20 Issue 1, p172 

    Sleep-disordered breathing (SDB) is prevalent in childhood obesity. It may be an independent risk factor for the metabolic syndrome. Possible mechanisms are inflammation and oxidative stress. Adenotonsillectomy in childhood obesity is associated with a high recurrence rate and risk of...

  • Endothelial dysfunction in obese non-hypertensive children without evidence of sleep disordered breathing. Bhattacharjee, Rakesh; Alotaibi, Wadha H.; Kheirandish-Gozal, Leila; Capdevila, Oscar Sans; Gozal, David // BMC Pediatrics;2010, Vol. 10, Special section p1 

    Background: Endothelial dysfunction is a complication of both obesity and obstructive sleep apnea syndrome (OSAS), the latter being highly prevalent among obese children. It is unknown whether obesity causes endothelial dysfunction in children in the absence of OSAS. This study examines...

  • Severity Assessment of Obstructive Sleep Apnea Syndrome (OSAS) in Pediatric Patients. Goroza, Edmund; Sagy, Mayer; Sagy, Noa; Bock, Kevin // Clinical Pediatrics;Jun2009, Vol. 48 Issue 5, p528 

    Objective. To assess obstructive sleep apnea syndrome (OSAS) severity among pediatric patients. Design. A retrospective review of charts and polysomnography (PSG) results. Measurements and main results. Apnea-hypopnea index (AHI) and the cumulative duration of sleep while O2SAT was <91% were...

  • Infant Snoring, Mental Development, and Cigarette Smoke Exposure. Montgomery-Downs, Hawley // Pediatrics for Parents;2007, Vol. 23 Issue 11, p10 

    The article evaluates the link between sleep-disordered breathing and children's behavior, learning, and memory function. Researchers found that among older children, learning was impaired by the presence of snoring. Living in household with someone who smoked did not increase the chances that...

  • Central sleep apnea in obese children with sleep-disordered breathing. Chou, C H; Kang, K T; Weng, W C; Lee, P L; Hsu, W C // International Journal of Obesity;Jan2014, Vol. 38 Issue 1, p27 

    Objectives:In contrast to obstructive sleep apnea (OSA), central sleep apnea (CSA) in obese children has received lesser attention. As pediatric CSA is more prevalent than expected and adversely impacts health, this study aims to elucidate the major factors associated with central apnea index...

  • IMPROVING OUTCOMES FOR CHILDREN with OSA. Murphy, Timothy D. // RT: The Journal for Respiratory Care Practitioners;Mar2009, Vol. 22 Issue 3, p38 

    The article focuses on the need to improve the diagnosis of obstructive sleep apnea (OSA) in children. It is stated that the primary cause of pediatric OSA is upper airway narrowing which is usually related to tonsillar and adenoidal hypertrophy. Details on the consequences of sleep...

  • Prevalence of obstructive sleep apnea in children and adolescents with sickle cell anemia. Salles, Cristina; Trindade Ramos, Regina Terse; Daltro, Carla; Barral, Andréa; Marinho, Jamocyr Moura; Matos, Marcos Almeida // Jornal Brasileiro de Pneumologia;nov2009, Vol. 35 Issue 11, p1075 

    Objective: To estimate the prevalence of obstructive sleep apnea syndrome (OSAS) in children and adolescents with sickle cell anemia (SCA); to investigate the possible correlation between mean annual hemoglobin level and total sleep time with SpO2 < 90%, as well as between mean annual hemoglobin...

  • Apnea-hypopnea indices and snoring in children diagnosed with ADHD: a matched case-control study. Galland, Barbara; Tripp, E.; Gray, Andrew; Taylor, Barry // Sleep & Breathing;Sep2011, Vol. 15 Issue 3, p455 

    Objectives: To measure apnea-hypopnea indices and snoring in children diagnosed with attention-deficit hyperactivity disorder (ADHD) in a case-control design. Additionally, the study design allowed us to investigate whether or not methylphenidate had any effect on breathing variables. Methods:...

  • Epilepsy and Sleep-Disordered Breathing as False Friends: A Case Report. Vitelli, Ottavio; Miano, Silvia; Tabarrini, Alessandra; Mazzotta, Anna Rita; Supino, Maria Chiara; Forlani, Martina; Villa, Maria Pia // Journal of Child Neurology;Oct2014, Vol. 29 Issue 10, pNP114 

    Because signs of nocturnal seizures can overlap with sleep respiratory events, clinicians can have difficulty distinguishing abnormal events related to sleep disorders from epileptic seizures. We describe the case of a 3-year-old child presenting with ictal electroencephalographic (EEG) activity...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics